Willy Chertman

Article

Willy Chertman is a recurring person in the Astral Codex Ten archive, appearing 4 times across 4 issues between October 31, 2022 and January 17, 2025. The archive places it in contexts such as “Willy Chertman writes : I’m pretty sure I reached the first Jhana a few yrs ago”; “But Willy Chertman has a long analysis of fertility trends here”; “Related article by Willy Chertman on how Slow, Costly Clinical Trials Delay Biomedical Breakthroughs”. It most often appears alongside Harvard, Scott, Twitter.

Metadata

  • Category: People
  • Mention count: 4
  • Issue count: 4
  • First seen: October 31, 2022
  • Last seen: January 17, 2025

Appears In

Source Context

Recovered passages from the original issue text. When the raw archive preserved outbound links inside the source passage, they are listed directly under the quote.

October 31, 2022 · Original source
Willy Chertman writes:
February 17, 2023 · Original source
This graph (source) shows pregnancy rate by sperm count per artificial insemination cycle. It seems to plateau around 30 million. An average ejaculation is 3 ml, so total sperm count is 3x sperm/ml. Since sperm/ml has gone down from 99 million to 47 million, total count has gone down from ~300 million to ~150 million. 150 million is still much more than 30 million, but sperm count seems to have a wide distribution, so it’s possible that some of the bottom end of the distribution is being pushed over the line where it has fertility implications. But Willy Chertman has a long analysis of fertility trends here, and concludes that there’s no sign of a biological decline. Either the sperm count distribution isn’t wide enough to push a substantial number of people below the 30 million bar, or something else is wrong with the theory. Levine et al model the sperm decline as linear. If they’re right, we have about 10 - 20 more years before the median reaches the plateau’s edge where fertility decreases, and about 10 years after that before it reaches zero. Developing countries might have a little longer. It feels wrong to me to model this linearly, although I can’t explain exactly why besides “it means sperm will reach precisely 0 in thirty years, which is surely false”. The authors don’t seem to be too attached to linearity, saying that “Adding a quadratic or cubic function of year to meta-regression model did not substantially change the association between year and SC or improve the model fit”. Still, the 2022 meta-analysis found that the trend was, if anything, speeding up with time, so it doesn’t seem to be obviously sublinear. How Long Has This Been Going On? The first recorded claim about declining sperm counts was in Nelson & Bunge, 1974. They noticed that sperm counts seemed to be declining since the first good study in 1951. There were some previous small unreliable studies before 1951 (the earliest was 1929) that seemed to get vaguely similar numbers to the 1951 study. So, very speculatively, one might suggest that sperm counts started declining between 1951 and 1974. See the next section for some problems with this story. How Sure Are We That This Is Even Real? Not too sure. The authors of these studies are well-respected scientists - yes, even the one who wrote the book about imperiling the future of the human race - and they seem to be doing good statistics. But an argument against might start with this graphic: Source: Figure 2 here. Each circle is an individual study examined in Levine’s first meta-analysis. I notice two things: Yes, okay, that line is pointing very slightly down, and apparently this is statistically significant.
June 01, 2023 · Original source
22: Related article by Willy Chertman on how Slow, Costly Clinical Trials Delay Biomedical Breakthroughs. Twitter discussion here.
January 17, 2025 · Original source
I agree with this solution. 3: Ruxandra Teslo and Willy Chertman: The Case For Clinical Trial Abundance 4: This month in nominative determinism: NYT article calculating your chance of winning the lottery, by Victor Mather (h/t Yafah Edelman). 5: Someone is working on a dating site that uses your conversations with Claude to find a match. Link here, although so far it’s just a landing page where you can register interest (h/t @venturetwins) 6: The Lyttle Lytton Contest searches for the worst possible opening line for a novel; it’s been going on since 2001 and this year’s results are in. 7: Gary Marcus and Miles Brundage have made a bet about AI progress. I agree with @tamaybes and others in saying that Miles let Gary off too easily; Gary’s public statements all sound like “modern AI is mostly hype, it doesn’t really do anything like thinking”, but the bet is about things like “will AI make a Nobel Prize caliber scientific discovery by 2027?” and “will AI write Pulitzer-quality books by 2027?” I don’t blame Gary for taking the best terms he could find. But I am worried that if AI makes a Nobel-quality scientific discovery in 2026, but doesn’t quite write the Pulitzer-quality book, then Gary will get to claim victory over the AI optimists, whereas in fact that would be at probably the 95th percentile of fast timelines by most people’s estimate. 8: “The probability that cows (or other non-human animals) are experiencing constant bliss, lack tanha (craving, aversion, and the resulting suffering), or are "enlightened by default" is, by my estimation, very low”. 9: Recursive Adaptation (blog on addiction policy)’s predictions for 2025. 75% of FDA approval of GLP-1 for a substance use disorder by 2029! 10: In my post on the economics of GLP-1 receptor agonists (eg Ozempic), I wrote about how they’re currently widely available because of a loophole suspending patents during a shortage, and predicted there would be a big fight when the shortage was over. Sure enough, the FDA tried to declare that the shortage of tirzepatide (a next-generation Ozempic relative) was over, compounding pharmacies sued, and tirzepatide is still available while the issue goes through the courts (and will the administration have an opinion?) Also, compounding pharmacy access startup Mochi says that they will continue to prescribe even if the shortage is over, using another loophole saying doctors can do this for specific individual patients in cases of medical necessity. This is an extremely fake use of this loophole, but will the government be willing to call their bluff? 11: Jacob Falkovich has a blog on dating advice, which he plans to turn into a book of dating advice. I can’t really comment on the accuracy (my dating strategy tends to look more like waiting for women to send me emails saying “I like your blog, would you like to go on a date?” which probably doesn’t generalize), but I’ve had many good interactions with Jake, and he has a beautiful family which means he must be doing something right. Also, Jake is poly, and I sometimes wonder if poly people are the only ones qualified to give dating advice: if you’re monogamous, you either met your future spouse quickly (in which case you have no experience), dated for years without meeting your spouse (in which case you can’t be very good), or aren’t looking for a committed relationship at all (which is just pickup artistry, and follows very different dynamics). Poly people are the only ones who can break out of this trilemma! 12: Christ And Counterfactuals is a blog on effective altruism from a Christian perspective. Some previous attempts at this have felt kind of forced, but the first post I read here was actually pretty interesting. Richard Swinburne (apparently “the world’s best Christian philosopher”), thinks that: “[One] reason why it is good that the human race should sometimes be in an initial situation of considerable ignorance about the causes and effects of our actions, is this. If God abolished the need for rational inquiry and gave us from childhood strong true beliefs about the causes of things, that would make it too easy for us to make moral decisions. As things are in the actual world, most moral decisions are decisions taken in uncertainty about the consequences of our actions. I do not know for certain that if I smoke, I will get cancer; or that if I do not give money to some charity, people will starve. So we have to make our moral decisions on the basis of how probable it is that our actions will have various outcomes—how probable it is that I will get cancer if I continue to smoke (when I would not otherwise get cancer), or that someone will starve if I do not give. Since probabilities are so hard to assess, it is all too easy to persuade yourself that it is worth taking the chance that no harm will result from the less demanding decision (the decision which you have a strong desire to make). And even if you face up to a correct assessment of the probabilities, true dedication to the good is shown by doing the act which, although it is probably the best action, may have no good consequences at all.” (Could a Good God Permit so Much Suffering? A Debate, pp. 52-53.) This is pretty galaxy-brained, but something galaxy-brained must be going on for God to tolerate the existence of evil at all, and this is a surprisingly natural extension of some common premises on the subject. 13: Swedish study: diagnosing the marginal patient with a psychiatric condition makes their life worse. Of the two mechanisms they looked at, stigma seems more involved than drug side effects. My opinion: this study was done on conscripts undergoing a mandatory psych evaluation for the army, who had no previous reason to think they had a psych disease and had not sought treatment. This is a different situation from somebody who comes to a psychiatrist asking for relief from specific symptoms they have noticed. Also, Sweden c. 2005 is a different culture from America 2025 in terms of how much stigma a psych diagnosis carries. I think it’s possible that if you never considered that you had psychiatric problems, and were suddenly given a diagnosis in 2005 Sweden and told you couldn’t serve in the army, that’s likely to destabilize your self-image more than a person who knows they’re depressed going to a psychiatrist in 2025 US and getting antidepressants. 14: RIP Felix Hill, research scientist at DeepMind and mentor to many in the AI community. You can read his suicide note here, though the obvious content warning applies. He says he took ketamine for mild anxiety and it plunged him into an incredibly deep depression that he couldn’t get out of; he leaves his story behind as a warning for others. I appreciate his warning, but I wish he had said more about what dose he used; different people’s ketamine doses vary by almost two orders of magnitude, I’d previously thought that the low doses were pretty safe and the high doses were sketchy, and I would like to know whether I should update or not. 15: RIP Max Chiswick, professional poker player, effective altruist, and ACX reader. 16: Adrian Dittman, a Twitter account widely accused of being Elon Musk’s alt, has been revealed to be . . . a guy named Adrian Dittman. Congrats to Maia Crimew and the Spectator for actually investigating this, unlike many other news sources which spread the Musk conspiracy theory. Also, the people involved got banned from X for some reason, maybe because this qualified as doxxing Dittman. 17: Related: Musk claims to be among the top players in the world at several computer games. A veteran Path of Exile gamer presents evidence that Musk faked his PoE2 accomplishments by hiring a Chinese guy to play on his account. Some Musk supporters in the comments suggest that maybe he hires the Chinese guy to level up his account, but his accomplishments (eg speedruns) are still his own? 18: Related: Sam Harris says he has been friends with Musk since 2008, but he noticed a sudden shift for the worse in his personality around 2020 which made it impossible to stay friends with him. He gives the example of Musk losing a bet with him that there would be 35,000+ COVID cases in the US, refusing to pay up, and launching personal attacks on Sam when asked to do so. What happened? Some theories: Musk turned right-wing, which ended his friendship with Sam for the same reason political differences have always ended friendships (but then what about the bet, which seems like objectively bad behavior?)