Minicircle

Article

Minicircle is a recurring organization in the Astral Codex Ten archive, appearing 3 times across 3 issues between September 04, 2023 and February 10, 2025. The archive places it in contexts such as “documentary on Minicircle, the biotech company in Prospera”; “Minicircle, the most famous biotech clinic currently in Prospera”; “Prospera-based weird biotech company MiniCircle”. It most often appears alongside California, California Forever, Dryden Brown.

Metadata

  • Category: Organizations
  • Mention count: 3
  • Issue count: 3
  • First seen: September 04, 2023
  • Last seen: February 10, 2025

Appears In

Source Context

Recovered passages from the original issue text. When the raw archive preserved outbound links inside the source passage, they are listed directly under the quote.

September 04, 2023 · Original source
Here’s a documentary on Minicircle, the biotech company in Prospera.
February 03, 2025 · Original source
It looks like a big part of investors’ hope for Prospera is biotech research and medical tourism. It hosted the Vitalia conference, and the Vitalia team are trying to build on it with Infinita, a charter city VC, and Viva, a broader program and potential more permanent hub.. I still think that Minicircle, the most famous biotech clinic currently in Prospera, is either confused or fraudulent, but hopefully they can eventually attract firms which are neither.
February 10, 2025 · Original source
1: I’ve previously cited some pretty compelling research that Prospera-based weird biotech company MiniCircle can’t work, but Micah Zoltu reports doing a study and finding that minicircles increased VEGF expression in some mice. A commenter notes that results are 1000x weaker than clinically significant levels, but Micah says he wasn’t dosing carefully and was just trying to find an effect at all, so maybe this could be solved by better dosing. I look forward to hearing more about his research (ie please email me when you have more results). I notice I am pattern matching this to things like EmDrive and LK-99 (amazing breakthrough that could change everything, comes from source which charitably is not the sort of people you would expect to make amazing breakthroughs, some people report positive results but never in perfect definitive tests), so I’m still very skeptical.