Pedro Silva
Article
Pedro Silva is a recurring person in the Astral Codex Ten archive, appearing 2 times across 2 issues between December 28, 2021 and November 04, 2022. The archive places it in contexts such as “Pedro Silva, $60,000, to use in silico reverse screening”; “Pedro Silva planned to use in silico screening to identify the biochemical targets of seven promising natural antibiotics”. It most often appears alongside 1DaySooner, ACX Grants, African Swine Fever.
Metadata
- Category: People
- Mention count: 2
- Issue count: 2
- First seen: December 28, 2021
- Last seen: November 04, 2022
Appears In
Related Pages
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- 1DaySooner (2 shared issues)
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- ACX Grants (2 shared issues)
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- African Swine Fever (2 shared issues)
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- Alex Hoekstra (2 shared issues)
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- Alice Evans (2 shared issues)
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- ALLFED (2 shared issues)
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- Allison Berke (2 shared issues)
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- Australia (2 shared issues)
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- Beny Falkovich (2 shared issues)
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- ClearerThinking.org (2 shared issues)
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- Crowdfight (2 shared issues)
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- Delia Grace (2 shared issues)
External Links
Source Context
Recovered passages from the original issue text. When the raw archive preserved outbound links inside the source passage, they are listed directly under the quote.
Pedro Silva, $60,000, to use in silico reverse screening and molecular dynamics simulations to discover the targets of seven promising natural antibiotics and to try to develop wider-spectrum derivatives. Antibiotic resistant infections kill a 5-6 digit number of people each year, and this is the kind of basic research that could lead to new drugs somewhere down the line.
1: Discover Molecular Targets Of Antibiotics (8/10) Pedro Silva planned to use in silico screening to identify the biochemical targets of seven promising natural antibiotics, which could potentially help develop better versions of them. He says he's finished most of the simulations and determined the 5-20 most stable complexes for each antibiotic. Once he finishes this, he can start additional simulations on the best complexes to obtain better estimates of their stability and construct hypotheses on which of these is most involved in the antibiotic's efficacy.