Alzheimer’s

Article

Alzheimer’s is a recurring concept in the Astral Codex Ten archive, appearing 2 times across 2 issues between August 20, 2021 and August 13, 2024. The archive places it in contexts such as “less amyloid, same Alzheimer’s”; “they’re also effective against stroke, heart disease, kidney disease , Parkinson’s , Alzheimer’s , alcoholism , and drug addiction”. It most often appears alongside FDA, ACT/SSC, aducanumab.

Metadata

  • Category: Concepts
  • Mention count: 2
  • Issue count: 2
  • First seen: August 20, 2021
  • Last seen: August 13, 2024

Appears In

Source Context

Recovered passages from the original issue text. When the raw archive preserved outbound links inside the source passage, they are listed directly under the quote.

August 20, 2021 · Original source
The true tragedy of Aduhelm will be that the Alzheimer's Disease research space, which had begun to move away from the amyloid-centric hypothesis, is being effectively redirected to amyloid once again. Research $$ and healthcare $$ will be redirected towards a drug target that has done nothing but fail in clinical trials for 20+ years. The amount of wasted research and pharma money will be mindboggling.
- Anecdotally, as someone who used to work in the Alzheimer's research space, nobody in the field seriously thinks the amyloid hypothesis is true. It's been tried, over and over again, every drug that's ever aimed at that mechanism has failed, it's busted.
I want to add another point: IMO, Aducanumab isn't shit, it's just that Alzheimer's is really really hard.
August 13, 2024 · Original source
...n. But only a small one. GLP-1 receptor agonist medications like Ozempic are already FDA-approved to treat diabetes and obesity. But an increasing body of research finds they’re also effective against stroke, heart disease, kidney disease , Parkinson’s , Alzheimer’s , alcoholism , and drug addiction . There’s a pattern in fake scammy alternative medicine. People get excited about some new herb. They invent a laundry list of effects: it improves heart health, softens...