EA

Article

EA is a recurring concept in the Astral Codex Ten archive, appearing 21 times across 21 issues between April 30, 2021 and July 03, 2025. The archive places it in contexts such as “rationality/EA-aligned folks like me”; “raise awareness about EA / ACX”; “Some rationalist/EA leaders are focusing on Boston”. It most often appears alongside Scott, Boston, Mexico.

Metadata

• Category: Concepts
• Mention count: 21
• Issue count: 21
• First seen: April 30, 2021
• Last seen: July 03, 2025

Appears In

• Your Book Review: The Wizard And The Prophet
• Meetups Everywhere 2021: Times And Places
• Boston Meetup This Sunday
• ACX Grants Results
• Open Thread 215
• Spring Meetups In Seventy Cities
• Highlights From The Comments On Criticism Of Criticism Of Criticism
• Meetups Everywhere 2022: Times & Places
• Highlights From The Comments On Billionaire Replaceability
• Spring Meetups Everywhere 2023
• Your Book Review: Lying for Money
• Meetups Everywhere 2023: Times & Places
• Highlights From The Comments On Kidney Donation
• In Continued Defense Of Effective Altruism
• Highlights From The Comments On Capitalism & Charity
• Spring Meetups Everywhere 2024
• Contra Stone On EA
• Highlights From The Comments On Nietzsche
• Links For December 2024
• Missing Heritability: Much More Than You Wanted To Know
• Highlights From The Comments On Missing Heritability

Related Pages

• • Scott (12 shared issues)
• • Boston (9 shared issues)
• • Mexico (9 shared issues)
• • Cambridge (8 shared issues)
• • effective altruism (8 shared issues)
• • India (8 shared issues)
• • London (8 shared issues)
• • Michael (8 shared issues)
• • ACX (7 shared issues)
• • Alex (7 shared issues)
• • Canada (7 shared issues)
• • Denmark (7 shared issues)

External Links

• • http://ClearerThinking.org
• • http://DarnAir.org
• • http://apartresearch.com
• • http://blog.nuclearsecrecy.com/2022/02/03/10-years-of-nukemap/
• • http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.182.5521&rep=rep1&type=pdf
• • http://clearerthinking.org
• • http://eadbatteries.substack.com
• • http://econfac.bsu.edu/research/workingpapers/bsuecwp200804gisser.pdf
• • http://example.com
• • http://facebook.com/EffectiveAltruismWellington
• • http://forum.effectivealtruism.org/posts/LJwGdex4nn76iA8xy/some-blindspots-in-rationality-and-effective-altruism
• • http://futuresearch.ai/

Source Context

Recovered passages from the original issue text. When the raw archive preserved outbound links inside the source passage, they are listed directly under the quote.

Your Book Review: The Wizard And The Prophet

April 30, 2021 · Original source

The fact that Vogt’s first entry into the public sphere is rallying the public against anti-malaria measures leaves a pretty bad taste in my mouth, as I’m sure it does for any of Mann’s Effective Altruist aligned readers. It would be one thing if Vogt were concerned about the detrimental impact of malaria on humans AND the detrimental impact of malaria prevention methods on bird life. But in subsequent chapters of Vogt’s biography, Mann goes out of his way to show that Vogt’s influences and contemporary members of the environmentalist milieu – for example, Madison Grant, co-founder of the Bronx Zoo, organizer of the United States national park system, and author of the charmingly named The Passing of the Great Race, beloved by Hitler – were, to put in mildly, extremely uninterested in the wellbeing of all humankind. Instead, they were obsessed by fears of an unchecked Malthusian population explosion, race mixing, and a resultant societal degeneration that could only be stopped by halting (read: starving out) population growth. Which people deserved to live in harmony with nature in the ensuing pastoral utopia and which would be relegated to the dustbin of history was not an exercise they left to the reader. Mann writes that Vogt, like his buddies, was "loudly scornful of the ‘unchecked spawning’ and ‘untrammeled copulation’ of ‘backward populations’ – people in India, he sneered, breed with ‘the irresponsibility of codfish.’"

Inline links: Madison Grant

Meetups Everywhere 2021: Times And Places

August 23, 2021 · Original source

SKOPJE, MACEDONIA (RSVP) Contact: Qantarot, info[at]kantarot[dot]mk Time: 5:00 PM, Wednesday, December 22 Location: Rooftop of the Intertec building in Skopje (outdoor but heated and covered in case of rain). Since you'll need to be let in, RSVPing is encouraged. You can also contact me the day of the meetup at +389 seven one 890 497. Coordinates: https://w3w.co/libraries.describe.fresh Notes: I run a blog that recently spun off a foundation. In Skopje we have a small but passionate rationality community that gravitates around my blog/foundation and we would love to grow the community and raise awareness about EA / ACX.

Inline links: RSVP, https://w3w.co/libraries.describe.fresh, a blog, a foundation

Boston Meetup This Sunday

September 04, 2021 · Original source

Some rationalist/EA leaders are focusing on Boston right now as a promising place to community-build. They’re especially trying to expand the student groups at Harvard and MIT. If you live in Boston and/or attend either of those colleges, then - whether or not you can make it Sunday - consider giving them your name through this form so they can help get you connected.

Inline links: this form

ACX Grants Results

December 28, 2021 · Original source

The Oxfendazole Development Group, $150,000, to develop oxfendazole. This is a next-generation antiparasitic drug which may one day replace albendazole and mebendazole, the current choices for deworming. Several hundred million children worldwide suffer from parasitic worm infections; this certainly affects their health, and a growing body of research suggests it might affect their cognitive ability, educational attainment, and future income. GiveWell endorses deworming as one of the most effective charitable interventions; the successful development of new antiparasitics would further this effort. Oxfendazole has done well in early studies and this group wants to follow them up in the hopes of eventually getting FDA approval. To learn more or send a donation, see this site

Inline links: The Oxfendazole Development Group, endorses deworming, this site

NA, $90,000, to buy a year of his time. NA is an experienced Australian political operative "on a first name basis with multiple federal politicians". You might remember some of his comments and stories from the ACX comment section, where he goes by AshLael. He's interested in using his expertise to promote effective altruism, either by lobbying directly or by training EAs in how to produce political change. I have no idea what to do with him right now but I am going to figure it out and then do it. If you're in EA and have a good idea how to use this opportunity, please let me know.

Inline links: comments and stories

The Effective Altruism Funds team handled most of the financial infrastructure for me. Thanks especially to Sam Deere, Jonas Vollmer, Helena Dias, and Chloe Malone for handling my increasingly frantic questions that I needed immediate responses to over the holiday season.

Inline links: Effective Altruism Funds team

Open Thread 215

March 13, 2022 · Original source

1: The effective altruist movement is offering $100,000 prizes to each of the top five new EA-aligned blogs this year. If you were thinking of writing a blog that touches on EA topics (x-risk, progress, global development, moral philosophy, AI, etc) now’s a pretty good time.

Inline links: is offering

Spring Meetups In Seventy Cities

April 10, 2022 · Original source

PORTLAND, OR Contact: Sam Celarek (support@pearcommunity.com) Date: April 24 Time: 4:00 PM Coordinates: https://plus.codes/84QVG9G7+XWG Location: 1548 NE 15th Ave, Portland, OR 97232 with a Large "PEAR" sign outside of the Building Notes: Call me (Sam) at 513-432-3310 if you can't find it. Please RSVP on Meetup or LessWrong so we can guesstimate food better. Group info: Portland Effective Altruism and Rationality is very active. We have book clubs, bi-weekly ai safety meet-ups, bi-weekly topical meet-ups, bi-weekly socials, and have an active Discord.

Inline links: https://plus.codes/84QVG9G7+XWG, Meetup, LessWrong, Portland Effective Altruism and Rationality, Discord

Highlights From The Comments On Criticism Of Criticism Of Criticism

July 28, 2022 · Original source

Last month, when I posted why I thought that a recent crime wave was because of anti-police protests, was that evanglizing? If I were Bahai, and I posted something about why I thought the Bahai religion was true, using the same style of argument, would that be evangelizing? If I posted my interesting thoughts about charity in 2005, and those happened to be the exact same thoughts that later became effective altruism, would I have been evangelizing then? If I write a post now about why you should all join EA, would that be evangelizing now?

Meetups Everywhere 2022: Times & Places

August 26, 2022 · Original source

BRISBANE, AUSTRALIA Contact: Jarred Filmer, jarred[dot]filmer[at]gmail[dot]com Time: Saturday, September 10, 7:00 PM Location: 52 McCaul Street Taringa (house) Coordinates: 5R4JFXXQ+P8 Event link(s): LessWrong, Facebook event Group info: We used to meet once a month years ago, but now just meet whenever there's a Meetups Everywhere :) Notes: Snacks will be provided but dinner will not be, would recommend eating before you come CANBERRA, AUSTRALIA Contact: Andy Bachler, Andy[dot]Bachler[at]gmail[dot]com Time: Wednesday, August 31, 5:30 PM Location: Badger & Co pub at ANU. Central location, parking free after 5pm, might be loud, sorry! Coordinates: 4RPFP4FC+34 Event link(s): LessWrong, Eventbrite Notes: Parking area just to the north of the pub, over the river, is free after 5pm! GOLD COAST (SOUTH), AUSTRALIA Contact: Lerancan, lerancan[at]gmail[dot]com Time: Sunday, September 11, 2:00 PM Location: A picnic table, Wyberba Street Reserve, Tugun Coordinates: 5R3MVF5W+555 Event link(s): LessWrong Notes: Email me in case of bad weather/you can't find me/you can't make that time etc. MELBOURNE, AUSTRALIA Contact: Ryan, xgravityx[at]hotmail[dot]com Time: Friday, September 2, 6:00 PM Location: Beer Deluxe Federation Square Coordinates: 4RJ65XM9+3Q Event link(s): LessWrong, Facebook event Group info: We're officially the Less Wrong Melbourne social meetup group, though our members include the broader rationalist community. We meet once a month for casual discussion (and beers for those so inclined). Please join our Facebook group to see the meeting invite; there you will see a WhatsApp group link - please join that group too to ensure timely updates in case of changes (Facebook notifications don't work reliably for this). Notes: Please RSVP to the meeting invite on the Facebook group so that I can make an appropriate booking. PERTH, AUSTRALIA Contact: Madge, madgech[at]gmail[dot]com Time: Sunday, September 25, 2:00 PM Location: Russell Square, Northbridge, corner of Shenton and Aberdeen St. There will be some sort of ACX meetup sign. Coordinates: 4PWQ3V34+W6 Event link(s): LessWrong, Facebook event Group info: I run one meetup per year, if someone else wants to take over please do Notes: Please RSVP on LessWrong or Facebook SYDNEY, AUSTRALIA Contact: Eliot, Redeliot[at]gmail[dot]com Time: Thursday, September 15, 6:00 PM Location: City of Sydney rsl, lvl 2 in the fishbowl Coordinates: 4RRH46F4+983 Event link(s): LessWrong, Meetup.com Group info: We meet monthly WOLLONGONG, AUSTRALIA Contact: Jason, jason[dot]bowkettblogs[at]gmail[dot]com Time: Saturday, September 3, 12:00 PM Location: UOW Library Coordinates: 4RQGHVVH+69 Event link(s): LessWrong CHENGDU, CHINA Contact: Alex, acx[dot]chengdu[at]gmail[dot]com Time: Thursday, September 15, 7:00 PM Location: Chef Wenwu Hot & Spicy Jianghu Food (Yulin store)/文武大厨·热辣江湖菜(玉林店). I (a foreigner) will be wearing a green shirt. Coordinates: 8P26J3C5+462 Event link(s): LessWrong Notes: Please RSVP at the above email address, I will give you my Wechat contact if you're interested in attending. Open to time/date/location changes, so let me know if the proposed event doesn't work for you! Can be a bilingual event; all welcome. 有双语交流的可能性。如果想来的话，请提前发给我个电子邮件。 HONG KONG Contact: Nathan, nathan[at]xevarion[dot]org Time: Saturday, September 10, 1:00 PM Location: The Catalyst, 2 Po Yan Street, Sheung Wan. Big wooden door. Coordinates: 862M74PW+6XP Event link(s): LessWrong BANGALORE, INDIA Contact: Nihal, propwash[at]duck[dot]com, Discord: propwash#4648 Time: Sunday, September 18, 4:00 PM Location: Matteo Coffea, Church Street Coordinates: 7J4VXJF4+PR Event link(s): LessWrong Group info: We're the longest active group in Asia — we've been meeting monthly for the last 4 years, discussing ACX posts, LW content with a diverse and friendly group of people. Check our website for more info. Notes: Please RSVP on LessWrong to help me be better prepared. HYDERABAD, INDIA Contact: Vatsal, vmehra[at]pm[dot]me, Whatsapp: +919944430856 (username: Vim) Time: Sunday, September 11, 5:00 PM Location: The Weekend Cafe, Plot No D, 3, Vikrampuri Colony, beside vac's bakery, Vikrampuri Colony, Lane, Secunderabad, Telangana, 500015, India Coordinates: 7J9WFF4X+5P Event link(s): LessWrong Group info: Our rationality meetup group has been around for about 3 months and we discuss articles and exercises (eg. CFAR handbook) that can help us improve epistemic and instrumental rationality. MUMBAI, INDIA Contact: PB, e2y94n1nv[at]relay[dot]firefox[dot]com Time: Sunday, October 9, 4:00 PM Location: Jamjar Diner, Versova Coordinates: 7JFJ4RM6+5W Event link(s): LessWrong Notes: Please RSVP on LessWrong or via email so I can plan activities accordingly. NEW DELHI, INDIA Contact: Suryansh Tyagi, suryanshtyagiphone[at]gmail[dot]com, WhatsApp/phone +919997299972 Time: Sunday, September 11, 5:00 PM Location: Select CityWalk Mall, Saket. Where inside the mall depends on the number of people interested. Coordinates: 7JWVG6H9+8H Event link(s): LessWrong Notes: Please either send me an email or message me on WhatsApp if you want to attend. Any suggestions/changes are welcome. UDAIPUR, RAJASTHAN, INDIA Contact: Shailendra Paliwal, acx-meetup-2022[at]shailendra[dot]me Time: Saturday, September 10, 7:00 PM Location: We'll be at Doodh Talai near Pichola Lake and I'll be wearing a gray t-shirt carrying a sign ACX Meetup Coordinates: 7JPMHM9M+HG Event link(s): LessWrong Notes: Please RSVP on LessWrong so that I can plan ahead UBUD, BALI, INDONESIA Contact: William Ubud, Napaproject[at]gmail[dot]com Time: Tuesday, August 30, 6:00 PM Location: PARQ Ubud Coordinates: 6P3QG789+F7 Event link(s): LessWrong TOKYO, JAPAN Contact: Harold Godsoe, hgodsoe[at]gmail[dot]com Time: Saturday, October 8, 10:00 AM Location: Near Nakameguro station - RSVP for details Coordinates: 8Q7XJPV2+QFP Event link(s): LessWrong, Meetup.com Notes: ACX Tokyo meets monthly since Sept 2021. Our meetups are in English, so far. To join in, feel free to get in touch in any of the many ways to do so (email, Meetup.com). It's useful to be in contact before coming to an event, to help with that first leap of faith. KUALA LUMPUR, MALAYSIA Contact: Yi-Yang, yi[dot]yang[dot]chua[at]gmail[dot]com, LessWrong profile Time: Saturday, September 17, 2:00 PM Location: I'll be in Lisette's Bangsar, which is a 5-minute walk from Bangsar LRT. I'll be wearing a pale green t-shirt and carrying an ACX sign. Coordinates: 6PM34MHH+VW Event link(s): LessWrong AUCKLAND, NEW ZEALAND Contact: Jonathan De Wet, jonpdw[at]gmail[dot]com Time: Saturday, September 3, 6:30 PM Location: 32 Stanley Ave Milford, Auckland Coordinates: 4VMP6QH4+86 Event link(s): LessWrong, Facebook event Notes: It’s a dinner party! Please RSVP on FB so I know how much food to make DUNEDIN, NEW ZEALAND Contact: Gavin, bisga673[at]student[dot]otago[dot]ac[dot]nz Time: Saturday, September 3, 3:00 PM Location: Picnic tables outside of St. David's lecture theatre on Otago University campus. I'll make a sign with ACX meetup. Coordinates: 4V6G4GP7+GM5 Event link(s): LessWrong Notes: There is no Dunedin group as far as I'm aware of, but I'd be keen to meet other likeminded people and organise group hangouts occasionally. WELLINGTON, NEW ZEALAND Contact: Ben W, benwve[at]gmail[dot]com Time: Tuesday, September 27, 5:30 PM Location: Rutherford House, Bunny Street, Wellington. Room MZ05, which is on the mezzanine floor Coordinates: 4VCPPQCH+FGC Event link(s): LessWrong Notes: We're running the event this time in partnership with Effective Altruism Wellington LAPU LAPU, CEBU, PHILIPPINES Contact: Dave, tokkolizard[at]tutanota[dot]com Time: Sunday, September 4, 2:00 PM Location: Starbucks in Mactan Newtown, there will be a sign with ACX MEETUP on it. Coordinates: 7Q268257+4F Event link(s): LessWrong Notes: Please RSVP by mail so I know if I need to set up a bigger meeting place SINGAPORE Contact: Jonathan Ng, jonathan[dot]ng1[at]gmail[dot]com, Telegram @derpy Time: Tuesday, September 6, 6:30 PM Location: Tanjong Pagar MRT gantry, I'll be wearing the dark blue EA Global 2022 jumper Coordinates: 6PH57RGW+J8 Event link(s): LessWrong

Inline links: 5R4JFXXQ+P8, LessWrong, Facebook event, 4RPFP4FC+34, LessWrong, Eventbrite, 5R3MVF5W+555, LessWrong, 4RJ65XM9+3Q, LessWrong, Facebook event, 4PWQ3V34+W6, LessWrong, Facebook event, 4RRH46F4+983, LessWrong, Meetup.com, 4RQGHVVH+69, LessWrong, 8P26J3C5+462, LessWrong, 862M74PW+6XP, LessWrong, 7J4VXJF4+PR, LessWrong, our website, 7J9WFF4X+5P, LessWrong, 7JFJ4RM6+5W, LessWrong, 7JWVG6H9+8H, LessWrong, 7JPMHM9M+HG, LessWrong, 6P3QG789+F7, LessWrong, 8Q7XJPV2+QFP, LessWrong, Meetup.com, Meetup.com, LessWrong profile, Lisette's Bangsar, 6PM34MHH+VW, LessWrong, 4VMP6QH4+86, LessWrong, Facebook event, 4V6G4GP7+GM5, LessWrong, 4VCPPQCH+FGC, LessWrong, 7Q268257+4F, LessWrong, 6PH57RGW+J8, LessWrong

CALGARY, AB Contact: David Piepgrass, qwertie256[at]gmail[dot]com Time: Saturday, September 10, 2:00 PM Location: Marlborough Mall food court Coordinates: 9538324C+CH9 Event link(s): LessWrong Group info: It's small! EDMONTON, AB Contact: JS, ⁨ta1hynp09[at]relay[dot]firefox[dot]com Time: Thursday, October 13, 6:30 PM Location: Polar Park Brewing Company - we will have a sign. Coordinates: 9558GG82+GG Event link(s): LessWrong Group info: LessWrong VANCOUVER, BC Contact: Tom Ash and Dirk Haupt, events[at]philosofiles[dot]com Time: Saturday, September 10, 1:00 PM Location: Dude Chilling (aka Guelph) Park, near the intersection of Main, Broadway & Kingsway. We'll be just west of the garden - look for Tom in a neon yellow shirt. Coordinates: 84XR7W73+PG Event link(s): LessWrong, Facebook event Group info: For future events, join the following: For rationalism, this Facebook group, for effective altruism, this Facebook group for both, Meetup.com Notes: ?? We'll have a sushi lunch for everyone who comes (fish or vegan). This is not at all necessary, but posting on the Facebook event to say you will or won't want this will help estimate numbers. RSVPing there will help boost attendance too. VICTORIA, BC Contact: Sarah McManus, sarahmcmanusbc[at]gmail[dot]com, Twitter @SarahAMcManus Time: Friday, September 23, 7:00 PM Location: Snowy Village, 4071 Shelbourne St #2a, Victoria, BC V8N 5Y1 - It's a small cafe, I'll be at a table with an ACX MEETUP sign on it Coordinates: 84WRFMG9+H3 Event link(s): LessWrong, Facebook event HALIFAX, NS Contact: Conor Barnes (ideopunk), conorbarnes93[at]gmail[dot]com Time: Sunday, September 25, 1:00 PM Location: Seven Bays Cafe (2017 Gottingen Street) Coordinates: 87PRMC29+9C Event link(s): LessWrong Notes: Join us at Seven Bayes KITCHENER-WATERLOO, ON Contact: Jenn, hi[at]jenn[dot]site Time: Sunday, September 25, 1:00 PM Location: Goudie's Lane, besides 8 Queen St N, Kitchener. I'll be wearing white boots and at one of the picnic tables if it's not raining, or further back in the parking area if it is. There will be some sort of ACX MEETUP sign. Coordinates: 86MXFG26+5CV Event link(s): LessWrong Group info: We have a new regular meetup group! We meet up every other Thursday. Events are posted on LessWrong, and we also have a website. Notes: Please RSVP on LessWrong if possible, but show up anyways if you weren't able to! Generally, past meetups everywhere events have attracted 8-15 people. OTTAWA, ON Contact: Tess Walsh, rationalottawa[at]gmail[dot]com Time: Friday, September 16, 6:00 PM Location: We are meeting at the Atelier d'innovation sociale, located at 95 Clegg St, K1S1C5. Specifically in the Lounge area, there will be numerous signs for ACX MEETUP where needed. Coordinates: 87Q6C84F+PM4 Event link(s): LessWrong, Facebook event Group info: We meet weekly on Friday evenings, and that allows us enough opportunity to try out a huge variety of different types of events — probably some that you, yes you, would enjoy! Here are our Facebook, LessWrong, and Discord (where the action really is) Notes: I always appreciate RSVP's in any form! It helps me set expectations/plan the best meetup I can! You can also contact me, Tess Walsh, with any questions whatsoever at rationalottawa@gmail.com TORONTO, ON Contact: Sean Aubin, seanaubin[at]gmail[dot]com Time: Sunday, September 18, 3:00 PM Location: Located at the picnic tables located in The Bentway, which is the sheltered area underneath the Gardiner Expressway. Coordinates: 87M2JHPR+X5W Event link(s): LessWrong Group info: Currently meeting monthly with ambitions to meet bi-monthly. Notes: Please RSVP on LessWrong so I know how many people to anticipate.

Inline links: 9538324C+CH9, LessWrong, 9558GG82+GG, LessWrong, LessWrong, 84XR7W73+PG, LessWrong, Facebook event, this Facebook group, this Facebook group, Meetup.com, 84WRFMG9+H3, LessWrong, Facebook event, 87PRMC29+9C, LessWrong, 86MXFG26+5CV, LessWrong, on LessWrong, a website, 87Q6C84F+PM4, LessWrong, Facebook event, Facebook, LessWrong, Discord, rationalottawa@gmail.com, 87M2JHPR+X5W, LessWrong

HUNTSVILLE, AL Contact: Mike, mjhouse[at]protonmail[dot]com Time: Saturday, September 3, 3:00 PM Location: Barnes & Noble – 300 The Bridge St #100, Huntsville, AL 35806. I'll be in the cafe with a sign that says ACX MEETUP on it. Coordinates: 866MP88H+53 Event link(s): LessWrong Notes: Barnes & Noble has an area for little kids. If you want to bring a service animal, that's probably fine, but I doubt they allow pets. PHOENIX, AZ Contact: Ben Morin, benjamin[dot]j[dot]morin[at]gmail[dot]com Time: Saturday, October 15, 1:00 PM Location: Thirsty Lion Pub in Tempe. I will have a table with an ACX sign. Coordinates: 8559FVVQ+6C Event link(s): LessWrong Group info: This will be our 5th meetup (started during the meetups everywhere last year). Notes: Please email if interested to be added to the email list, even if you can't make this event BELMONT, CA Contact: Moshe Z., belmont-acx[at]devskillup[dot]com Time: Sunday, September 4, 2:00 PM Location: Twin Pines Park, Picnic Tables. The table will have some sign saying 'ACX Meetup' on it. Coordinates: 849VGP8C+RRG Event link(s): LessWrong Group info: You can join the mailing list here. BERKELEY, CA Contact: Scott Time: Sunday, September 18, 1:00 PM Location: Rose Garden Inn, a rationalist event space at 2740 Telegraph Ave. Come in through the front gate on Telegraph. Coordinates: 849VVP5R+X7V Event link(s): LessWrong Group info: The Bay rationality community has a mailing list, a Discord server, and a Facebook group. There are dinner meetups every Thursday at 7 PM in the East Bay, and occasional meetups in SF and South Bay. FILLMORE, CA Contact: Ryan, wiserd[at]gmail[dot]com, Discord: Wiserd#0906 Time: Saturday, October 1st, 6:00 PM Location: It's my house. There are a bunch of plants on the porch and garbage bins in the driveway. Coordinates: 856393VX+VQ Event link(s): LessWrong Notes: Please RSVP to my email or Discord. Kids and dogs are welcome in the back yard. Full vaccinations (on the honor system) and masks required. GRASS VALLEY, CA Contact: Max Harms, raelifin[at]gmail[dot]com Time: Saturday, September 10, 2:00 PM Location: Condon Park by the prospector statue. In the case of rain we'll change the location to a residence, so RSVP to get updated! Coordinates: 84FW6W8H+C5 Event link(s): LessWrong IRVINE, CA Contact: Nick C, cohenskijanuary1[at]mail[dot]com Time: Saturday, October 1, 2:00 PM Location: University Town Center Coordinates: 8554M526+7H Event link(s): LessWrong Group info: We meet once a month at the same location. LOS ANGELES, CA Contact: Vishal Prasad (koreindian), vprasadcs[at]gmail[dot]com, Contact me on Discord. I am "Vishal" on the server. Time: Saturday, October 8, 6:30 PM Location: 11841 Wagner St., Culver City, CA 90039 Coordinates: 8553XHWM+GP Event link(s): LessWrong Group info: We meet weekly every Wednesday. We have been around for over 8 years. We discuss articles, watch movies, lift weights. We have a Discord server, a LessWrong group, and a website! Notes: Please RSVP on LessWrong so I know how much food to get. NEWPORT BEACH, CA Contact: Michael M, michaelmichalchik[at]gmail[dot]com Time: Saturday, August 27, 2:00 PM Location: Picnic tables next to 1900 Port Carlow community clubhouse. The park is verdant and pleasant and easy to access. Free street parking nearby. In case of bad weather, we have a couple of near by places to relocate to. Coordinates: 8554J48R+WCX Event link(s): LessWrong, Facebook event Group info: We will meet most Saturdays at 2pm until whenever. There will be short suggested readings and question most weeks to spur conversation, but they are optional. Each week we will ask if people have had something happen recently that surprised them or changed the way they looked at the world. Something that should or did update their priors. Participation is optional. Notes: Its a public park with tables and BBQ's so you can bring food and well behaved pets. We may regularly go on casual walks in the surrounding area. SAN DIEGO, CA Contact: Julius, julius[dot]simonelli[at]gmail[dot]com Time: Sunday, October 9, 3:00 PM Location: We will meet up in Bird Park. I will be wearing a red shirt. Coordinates: 8544PVQ8+Q7 Event link(s): LessWrong, Meetup.com Group info: Join our Discord server SAN FRANCISCO, CA Contact: Derek Pankaew, derekpankaew[at]gmail[dot]com Time: Sunday, September 18, 11:00 AM Location: We'll between in the Panhandle, between Ashbury and Masonic, with a 'ACX' sign. Coordinates: 849VQHC3+V8 Event link(s): LessWrong SAN JOSE, CA Contact: David Friedman, ddfr[at]daviddfriedman[dot]com Time: Saturday, September 17, 2:00 PM Location: 3806 Williams Rd, San Jose, CA 95117 Coordinates: 849W825J+6P Event link(s): LessWrong Group info: Before Covid we hosted every month or two. No structure, just conversation and food. We feed everyone who is still there at dinner time. We have done it once or twice since Covid. I have an email list of interested people. Notes: Kids are welcome. Please RSVP to my email so I will have a rough count of how many we are feeding. SAN MARCOS, CA Contact: Eric F., EricF14159[at]gmail[dot]com Time: Sunday, September 25, 2:00 PM Location: Hollandia Park Soccer Field. At the tables near the top parking lot. Coordinates: 85544VW4+RV Event link(s): LessWrong BOULDER, CO Contact: Josh Sacks, josh[dot]sacks+acx[at]gmail[dot]com Time: Sunday, October 16, 3:00 PM Location: 9191 Tahoe Ln, Boulder, CO 80301 Coordinates: 85GP2V96+JQ Event link(s): LessWrong Notes: Please RSVP on LessWrong so we know ~ how many people to expect! CARBONDALE, CO Contact: Nick, naj[at]njarboe[dot]com Time: Saturday, September 3, 1:00 PM Location: Sopris Park - Center covered picnic tables - blue shirt with ACX sign on table Coordinates: 85FJ9QXP+QMF Event link(s): LessWrong DENVER, CO Contact: Ian Philips, iansphilips[at]gmail[dot]com, Discord: palebone#2796 Time: Sunday, October 2, 11:00 AM Location: We'll be in the backyard patio of St. Mark's Coffee House. I'll wear a white shirt with (my brothers') baby faces on it and have a brown hat on. Coordinates: 85FQP2VP+9R Event link(s): LessWrong Group info: We meet typically 4 times a year. LAKEWOOD, CO Contact: Steven Zuber, stevenjzuber[at]gmail[dot]com Time: Wednesday, October 5, 7:00 PM Location: We meet in the clubhouse located in this townhome community: 8769 W Cornell Ave Lakewood, CO 80227 Coordinates: 85FPMW64+MW Event link(s): LessWrong, Meetup.com Group info: We meet the first Wednesday of every month. Informal, casual atmosphere with occasional presentations by people. Notes: Check the Meetup page or Facebook group for updates. FAIRFIELD, CT Contact: Justin Barclay, barclay[dot]justin[at]gmail[dot]com Time: Saturday, September 10, 10:00 AM Location: South Pine Creek Beach. I'll set up near the lifeguard stand. Coordinates: 87H84PCH+CM Event link(s): LessWrong MANCHESTER, CT Contact: Mike, park-mike[at]outlook[dot]com Time: Saturday, September 17, 5:00 PM Location: Near flagpole on top of hill Coordinates: 87H9QFFH+J7 Event link(s): LessWrong NEW HAVEN, CT Contact: RM, acx[dot]meetup[dot]nhv[at]gmail[dot]com Time: Sunday, September 18, 12:30 PM Location: Cross Campus (Yale University), New Haven, CT 06511. We'll be on the grass on the northern half of Cross Campus, closest to Sterling Memorial Library. I'll be wearing an orange shirt. Coordinates: 87H9836C+8VG Event link(s): LessWrong Notes: Feel free to bring friends! The vibe will be welcoming and relaxed, and you can stay for any amount of time. Please email me if you're thinking about coming so I can get the right number of Insomnia cookies! WASHINGTON, DC Contact: John Bennett, WashingtonDCAstralCodexTen[at]gmail[dot]com Time: Saturday, September 17, 6:00 PM Location: Froggy Bottom Pub: 2021 K Street NW, Washington, D.C. 20006 Coordinates: 87C4WX33+3J Event link(s): LessWrong, Facebook event Group info: The Washington DC ACX/SSC group has been active since the first Meetups Everywhere in 2017. We have Monthly Socials downtown, hikes, board game days, and other cultural events. We're looking to spin up more rationality Dojo-type events with nearby groups in the coming months. Notes: We've rented out the Froggy Bottom Pub for the night, dinner and soft drinks will be provided. Alcohol available for purchase if desired, but no purchases are required. Metered street parking on nearby blocks is free after 6:30. Closest Metros are Farragut West and Farragut North. CAPE CORAL / FORT MYERS, FL Contact: Shawn Spilman, shawn[dot]spilman[at]outlook[dot]com, 508 655 8123 Time: Sunday, October 2, 1:00 PM Location: 929 SW 54th Ln, Cape Coral, FL 33914 Coordinates: 76RWH224+44 Event link(s): LessWrong Notes: RSVP via email. I can be flexible about the date. GULF BREEZE / PENSACOLA, FL Contact: Christian, christian[dot]h[dot]williams[at]gmail[dot]com Time: Wednesday, October 12, 7:30 PM Location: The Bridge Bar - 33 Gulf Breeze Pkwy A, Gulf Breeze, FL 32561 Coordinates: 862J9RCF+G6 Event link(s): LessWrong Notes: Please RSVP by emailing me. Thanks! If I don't hear from anyone, I won't be there. I work for Metaculus, but promise not to talk your ear off about forecasting. (Unless you want it talked off.) MIAMI, FL Contact: Eric Magro, eric135033[at]gmail[dot]com, Discord: eric135#4943 Time: Sunday, September 11, 5:00 PM Location: Buckminster Fuller Fly's Eye Dome 140 NE 39th St #001, Miami, FL 33137 ----- Look for a paper sign on a table that says ACX MEETUP west of the dome. Coordinates: 76QXRR65+V2 Event link(s): LessWrong Group info: Miami ACX started in 2017. Our official meetup happens monthly in either Miami or Broward. There are activities happening on a weekly basis from Miami to Palm Beach. We have a Facebook group, Discord server, and Meetup.com group. ORLANDO, FL Contact: Noah Topper, noah[dot]topper[at]gmail[dot]com Time: Friday, September 16, 7:00 PM Location: 4000 Central Florida Blvd, Orlando, FL. We'll be meeting up at UCF's pavilion near Garages A and I. I'll have a pretty ACX Meetup sign. Coordinates: 76WWJQ2X+82 Event link(s): LessWrong Group info: We try to meet up once a month, so far they've just been casual social meetups with natural discussions of rationality topics. Here's our Discord link :) Notes: RSVPs on LessWrong would be greatly appreciated. :) TALLAHASSEE, FL Contact: JF, jf19o[at]fsu[dot]edu Time: Monday, August 29, 2:00 PM Location: Landis, FSU. I will be wearing a black shirt Coordinates: 862QCPR3+PX Event link(s): LessWrong ATHENS, GA Contact: Dallon, knox[dot]dallon[dot]a[at]gmail[dot]com, Discord: leonard#4208 Time: Saturday, October 15, 3:00 PM Location: Hendershots on Prince Avenue Coordinates: 865RXJ68+2W Event link(s): LessWrong Notes: I might bring some board games ATLANTA, GA Contact: Steve French, steve[at]digitaltoolfactory[dot]net Time: Saturday, September 17, 2:00 PM Location: Bold Monk Brewing - 1737 Ellsworth Industrial Blvd NW suite d-1 · Atlanta, GA (upstairs – look for the ACX Atlanta sign) Coordinates: 865QRH2F+V8 Event link(s): LessWrong, Meetup.com Group info: We've been in existence for four years – we have a dedicated crew and a very active Slack group Notes: Please RSVP on LessWrong or Meetup.com HONOLULU, HI Contact: Matt Popovich, mattpopovich[at]outlook[dot]com Time: Saturday, September 3, 4:00 PM Location: We'll meet at Magic Island at Ala Moana Beach Park, 1201 Ala Moana Blvd, Honolulu, HI 96814. From the parking lot, walk along the left side of the peninsula out toward Magic Island Lagoon. We're usually near the end of the peninsula, somewhere around the bathroom building. Look for the large 'ACX' sign. Coordinates: 73H475M3+JP Event link(s): LessWrong, Meetup.com Group info: Honolulu Rationality hosts discussion meetups about twice a month in Ala Moana Beach Park. Check us out on our website BOISE, ID Contact: Julia and John, jae[dot]miomu[at]gmail[dot]com Time: Friday, October 7, 6:00 PM Location: Old Timer's Shelter in Ann Morrison Park. I will have an ACX sign. Coordinates: 85M5JQ6P+96 Event link(s): LessWrong Notes: Please RSVP and feel free to bring kids. CHAMPAIGN-URBANA, IL Contact: Ben, cu[dot]acx[dot]meetups[at]gmail[dot]com Time: Friday, September 9, 7:00 PM Location: Siebel Center for Computer Science, Room 4403 Coordinates: 86GH4Q7G+H8F Event link(s): LessWrong Group info: Discord server Notes: RSVPs are appreciated but not at all required. You can RSVP by email or by pinging me in the Discord server. Suggested entrance is the East side of the building (see Coordinates) - we'll try to make sure at least that door is unlocked, but if it isn't then ping us on email or Discord. CHICAGO, IL Contact: Todd, info[at]chicagorationality[dot]com, https://chicagorationality.com/ Time: Sunday, September 18, 1:00 PM Location: Grant Park - North side of Balbo between the tracks and Columbus Coordinates: 86HJV9FH+84 Event link(s): LessWrong Group info: Chicago Rationality does a monthly discussion meetup (typically the first Saturday of the month) and a monthly social meetup (typically the third weekend of the month) Notes: Sign up for our email list to be notified of future meetups EVANSTON, IL Contact: Uzair, uzairq93[at]gmail[dot]com Time: Saturday, October 1, 7:00 PM Location: 626 Church Street, Evanston IL 60201 Coordinates: 86JJ28X9+5WQ Event link(s): LessWrong Notes: The venue is a pub but it's really more of a restaurant, big long tables available so space should be fine and non drinkers shouldn't feel too out of place. BLOOMINGTON, IN Contact: Avery, acxbloomington[at]fastmail[dot]com Time: Sunday, October 16, 2:00 PM Location: Switchyard Park. Will be at one of the tables near the Rogers Street parking lot. I will bring a cardboard sign that says “ACX”. Coordinates: 86FM4FX6+4Q Event link(s): LessWrong Group info: We met last year for Meetups Everywhere and it was fun! Here's a link to our Discord. Notes: You can RSVP via Discord or email, but you are encouraged to show up even if you did not RSVP! WEST LAFAYETTE, IN Contact: NR, mapreader4[at]gmail[dot]com Time: Saturday, September 17, 1:00 PM Location: 1275 1st Street, West Lafayette, IN 47906. We'll be in the south of the Earhart Hall lobby (not the dining court) near the piano, and I will be wearing a green shirt and carrying a sign with ACX MEETUP on it. Coordinates: 86GMC3GG+728 Event link(s): LessWrong LEXINGTON, KY Contact: Nathan, nwculley[at]gmail[dot]com Time: Saturday, September 3, 7:00 PM Location: Blue Stallion Brewing. 610 W. 3rd St., Lexington, KY 40508. We will have a sign indicating we are the ACX meetup. Coordinates: 86CQ3F4X+VF Event link(s): LessWrong Group info: We meet 1-2 times a month to talk about ACX, books, memes, etc., often over drinks and board games. NEW ORLEANS, LA Contact: Blake, blake[at]philosophers[dot]group Time: Sunday, September 4, 11:11 AM Location: Petite Clouet Cafe. Look for the group with an iPad that has a People’s Pint sticker. Coordinates: 76XFXX73+8R Event link(s): LessWrong Group info: Website Notes: Hybrid in-person and online, video link sent weekly. Email for the link. BOSTON, MA Contact: Robi Rahman, robirahman94[at]gmail[dot]com, 7039818526 Time: Saturday, September 10, 5:00 PM Location: Boston Common, at the Parkman Bandstand gazebo Coordinates: 87JC9W3M+PR Event link(s): LessWrong, Facebook event Group info: Mailing list, Facebook group, Meetup.com Notes: We'll be providing food at the meetup, and giving out free books related to ACX, rationality, and effective altruism. Email the hosts if you'd like a particular book or you have any dietary restrictions. Our group is also doing a tour of the JFK Presidential Library on September 9, you’re welcome to join! NORTHAMPTON, MA Contact: Alex, alex[at]alexliebowitz[dot]com Time: Friday, September 9, 6:00 PM Location: The Deck, 125A Pleasant St., Northampton MA 01096. The official address is bizarre and inaccurate; it's the outdoor dining part of a group of bars & restaurants in a former rail station... a whole block away from Pleasant St. The simplest way to get to The Deck is to enter The Platform, one of the other restaurants, by its street entrance around 36 Strong Ave., here (make sure to look at street view). Go inside and ask them to show you to The Deck. We'll have a sign. Coordinates: 87J9899F+H7H Event link(s): LessWrong, Facebook event Group info: We started in the 2018 Meetups Everywhere and is still going strong. We aim to meet about once every two weeks. At most meetups we get about 5-7 people out of a rotation of 15-20; Meetups Everywhere and other special events tend to bring in a few more than usual. We're a totally social meetup with no 'format' or suggested readings. Although it's not rare for us to touch on ACX articles and related topics, the conversation varies wildly, and you are welcome even if you're the most occasional ACX reader. Notes: We have a (not very active) Discord where you can DM me or post on a public channel. I'm most responsive by email. There is a small chance we'll have to change the location to somewhere else in Northampton. Please check the Less Wrong or Facebook posts on or after August 26 to get the final word on location. BALTIMORE, MD Contact: Rivka, rivka[at]adrusi[dot]com Time: Sunday, September 11, 7:00 PM Location: UMBC outside of the Performing Arts and Humanities Building, on the north side. I will have a sign that says ACX meetup. Parking is free on the weekends. Edit: Rain is forecasted; if it’s raining, we will be inside of the Performing Arts building, on the ground floor just inside the entrance. Coordinates: 87F5774P+53 Event link(s): LessWrong Group info: We meet Sundays at 7pm — half are in person and half are virtual. Notes: There will be pizza and drinks DETROIT, MI Contact: Matt Arnold, matt[dot]mattarn[at]gmail[dot]com Time: Tuesday, September 20, 7:00 PM Location: Tenacity Craft, 8517 2nd Ave, Detroit, MI 48202 Coordinates: 86JR9WG9+R6 Event link(s): LessWrong MINNEAPOLIS, MN Contact: Timothy, tmbond[at]gmail[dot]com Time: Saturday, September 10, 1:00 PM Location: Meet at the picnic tables near the southeast corner of Powderhorn Park - the ones by the parking lot. I will be wearing a green Google t-shirt and have a sign that says ACX. Coordinates: 86P8WPRW+76 Event link(s): LessWrong Notes: I will bring some snacks (but not a full lunch, so eat before or bring something if you'll be that hungry). Please RSVP on LessWrong. KANSAS CITY, MO Contact: Alex, alex[dot]hedtke[at]gmail[dot]com Time: Friday, September 16, 6:30 PM Location: We will be in the courtyard above Whole Foods (which is also an apartment complex). You can enter through the apartment lobby, located on Oak Street. We will have runners shepherding people from the entrance up to the courtyard. Coordinates: 86F72CM8+RR Event link(s): LessWrong, Meetup.com SAINT LOUIS, MO Contact: JohnBuridan, littlejohnburidan[at]gmail[dot]com Time: Saturday, October 8, 1:00 PM Location: Lily Pond Shelter, Tower Grove Park, St. Louis Coordinates: 86CFJP4R+XV Event link(s): LessWrong Notes: BYOB WEST PLAINS, MO Contact: Liam, liamhession[at]gmail[dot]com Time: Saturday, September 17, 12:00 PM Location: 10/40 Coffee, 24 Court Square, West Plains, MO Coordinates: 868CP4HW+CV Event link(s): LessWrong Notes: Hoping to get anyone from around the Ozark region DURHAM, NC Contact: Will Jarvis, willdjarvis[at]gmail[dot]com Time: Thursday, September 8, 7:30 PM Location: Ponysaurus Brewing Company, 219 Hood St, Durham Coordinates: 8773X4Q3+QW Event link(s): LessWrong Group info: We meet weekly! We also have a Discord LAKEWOOD, NJ Contact: Ben L, mywebdev3[at]gmail[dot]com Time: Saturday, October 29, 8:30 PM Location: TBD Event link(s): LessWrong MORRISTOWN, NJ Contact: Matt, matt[dot]brooks[at]impactmarkets[dot]io, Discord: Matt B#0216 Time: Saturday, October 1, 2:00 PM Location: 10 N Park Pl, Morristown, NJ 07960 (at the center of the Morristown Green) Coordinates: 87G7QGW9+RJ Event link(s): LessWrong Group info: This is the first meetup, come be a founding member of the Northern NJ ACX/EA/LW group! PRINCETON, NJ Contact: Danny K, dskumpf[at]gmail[dot]com Time: Saturday, October 1, 3:00 PM Location: Palmer Square, Princeton, NJ 08540. On the green right outside The Bent Spoon and Rojo's Roastary, near the big tree. I'll have some sort of ACX Meetup sign! Coordinates: 87G7982Q+2CP Event link(s): LessWrong LAS VEGAS, NV Contact: Jonathan Ray, ray[dot]jonathan[dot]w[at]gmail[dot]com Time: Sunday, September 11, 11:45 AM Location: At El Segundo Sol restaurant with giant ACX MEETUP signs Coordinates: 85864RHJ+3H Event link(s): LessWrong, Facebook event Group info: We meet regularly and mostly just socialize. We have a new Discord server. RENO, NV Contact: Steven, stevenl451[at]gmail[dot]com, Discord: Steeven#7407 Time: Friday, September 2, 5:30 PM Location: We'll be in Crissie Caughlin Park, near the tables and the swing set Coordinates: 85F2G46W+FG Event link(s): LessWrong Notes: Feel free to bring kids/dogs and please RSVP on LessWrong if you are going BUFFALO, NY Contact: George Herold, ggherold[at]gmail[dot]com Time: Sunday, September 11, 1:00 PM Location: 932 Welch Rd. Java Center, NY 14082 Coordinates: 87J3W467+8P Notes: Last-minute location change! LONG ISLAND, NY Contact: Gabe, gabeaweil[at]gmail[dot]com Time: Thursday, October 27, 7:00 PM Location: Whales Tale in Northport Coordinates: 87G8VJRW+99 Event link(s): LessWrong NEW YORK CITY, NY Contact: Jasmine, jasminermj[at]gmail[dot]com Time: Sunday, September 11, 4:00 PM Location: Pavillion @ Rockefeller Park, Warren St / River Terrace Coordinates: 87G7PX9M+4J3 Event link(s): LessWrong Group info: OBNYC has a Discord and a Google Group; the Google Group is the main mailing list we use for events NEWBURGH, NY Contact: Pedro David Bonilla, proportionatetoevidence[at]gmail[dot]com, Cell 8452001681 Time: Saturday, September 24, 10:00 AM Location: Perkins Restaurant & Bakery, 1421 NY-300, Newburgh, NY 12550 Coordinates: 87H7GWCH+GF Event link(s): LessWrong ROCHESTER, NY Contact: Skivverus, skivverus[at]gmail[dot]com, Discord: Skivverus#5915 Time: Saturday, October 8, 1:00 PM Location: 4870 Culver Road; will be wearing a polo shirt, jeans, and glasses, and may or may not have figured out a sign due to just getting back from honeymoon. Look for a pair of parrots, one white, one green with a yellow/orange head. Coordinates: 87M46FM6+Q5P Event link(s): LessWrong Notes: Venue very near amusement park; non-bathroom, non-parking amenities are therefore available but not free. Plan accordingly. Not particularly attached to specific location named, just happen to live reasonably close to there; alternative suggestions acceptable. Canadian visitors also welcome should your logistics permit; airport transportation available. RSVP via Discord preferred, but email will also work. CLEVELAND, OH Contact: Jack Zhang, LukeZhao9[at]protonmail[dot]com Time: Saturday, September 24, 1:00 PM Location: Picnic tables at Wade Oval (university circle) Coordinates: 86HWG96Q+GC5 Event link(s): LessWrong COLUMBUS, OH Contact: Daniel, daniel[dot]m[dot]adamiak[at]gmail[dot]com Time: Saturday, September 17, 3:00 PM Location: Jeffrey Park - Clinton Shelter. I will be wearing a red shirt. Coordinates: 86FVX3C3+QF Event link(s): LessWrong Group info: We meet once a month. We discuss EA, AI and other two letter initialisms. Occasionally we go for walks in local grottos and nature trails. Notes: Email me if you want to be added to the mailing list to receive any updates or future invites. RSVPing is appreciated. TOLEDO, OH Contact: Scout, scout[dot]sivar[at]gmail[dot]com Time: Saturday, September 10, 12:00 PM Location: Black Kite Coffee Coordinates: 86HRMCCV+9R Event link(s): LessWrong OKLAHOMA CITY, OK Contact: bean, battleshipbean[at]gmail[dot]com Time: Sunday, October 9, 1:00 PM Location: Edmond Public Library/Shannon Miller Park. I will be wearing a hat that says USS Iowa on it. Coordinates: 8674MG3C+MW Event link(s): LessWrong Group info: Had four people last year and a good time, moved to Edmond because a lot of us are up here. ALBANY, OR Contact: Kenan (he/him), kbitikofer[at]gmail[dot]com Time: Saturday, October 1, 2:00 PM Location: Bowman Park, Albany, Oregon. In or near the shelter. I will wear a bright red shirt and carry a sign with ACX MEETUP on it. Coordinates: 84PRJWR7+XC6 Event link(s): LessWrong CORVALLIS, OR Contact: Ethan Ashkie, ethanashkie[at]gmail[dot]com Time: Wednesday, September 7, 6:00 PM Location: Common Fields, in the reserved outdoor seating near the entrance Coordinates: 84PRHP5P+VQ Event link(s): LessWrong EUGENE, OR Contact: Ben Smith, benjsmith[at]gmail[dot]com Time: Wednesday, August 31, 7:00 PM Location: The Barn Light, 924 Willamette St, Eugene 97401 Coordinates: 84PR2WX4+VV Event link(s): LessWrong Notes: Please RSVP on LessWrong so I know how much pizza to get, but if you forget, don't worry about it, we want you to come along anyway PORTLAND, OR Contact: Sam F Celarek, support[at]pearcommunity[dot]com, 513-432-3310, Discord: Sam Celarek#2845 Time: Friday, September 9, 5:00 PM Location: 205 NW 4th Ave Coordinates: 84QVG8FG+V4 Event link(s): LessWrong, Meetup.com Group info: Portland Effective Altruism and Rationality is very active. We have book clubs, bi-weekly AI safety meet-ups, bi-weekly topical meet-ups, bi-weekly socials, and have an active Discord. Notes: We would prefer you RSVP on Meetup.com a week beforehand so that we can get the right amount of food! HARRISBURG, PA Contact: Phil, acxharrisburg[at]gmail[dot]com Time: Saturday, September 24, 2:00 PM Location: Ever Grain Brewing Co, 4444 Carlisle Pike, Camp Hill, PA 17011 - We will be sitting at one of the picnic tables outside with an ACX MEETUP sign Coordinates: 87G562QQ+8P Event link(s): LessWrong Group info: Small monthly meetup group based out of Harrisburg - celebrating 1 year of actuality! You can see more of our events on LessWrong. INDIANA, PA Contact: Eric, ericindianapa[at]gmail[dot]com, 717-256-2717 Time: Saturday, September 24, 11:00 AM Location: Caffè Amadeus in downtown Indiana, PA. I will have a sign with 'ACX Meetup' on one of the tables. Coordinates: 87G2JRFX+48 Event link(s): LessWrong Notes: Please RSVP via email or text message so I know how many to expect. PHILADELPHIA, PA Contact: Wes and Diana, rationalphilly[at]gmail[dot]com Time: Thursday, September 22, 6:30 PM Location: The Philadelphia Ethical Society, 1906 Rittenhouse Square. The meeting room is in the basement, look for the signs. Coordinates: 87F6WRXG+FQ Event link(s): LessWrong Group info: We tend to meet in downtown Philly on the last Thursday of the month. We're aiming to make the Ethical Society our new steady location. We have many links: Discord, Google Calendar, Facebook, Meetup, Google Group Notes: We'll be ordering food from a local restaurant, so no need to eat first. BYOB PITTSBURGH, PA Contact: Justin, pghacx[at]gmail[dot]com Time: Saturday, September 24, 2:00 PM Location: Westinghouse Shelter @ Schenley Park (W Circuit Rd near Schenley Dr). We have the outdoor shelter reserved, so light rain shouldn't be a problem, but in the event of extreme weather, we may relocate indoors (our default 'contingency indoor location' is Crazy Mocha Coffee on 2100 Murray Ave in Squirrel Hill). Coordinates: 87G2C3Q4+773 Event link(s): LessWrong Group info: We meet monthly-ish for general discussion and chit-chat, email me if you'd like to be notified of future meetups. STATE COLLEGE, PA Contact: John Slow, auk480[at]psu[dot]edu Time: Thursday, September 8, 5:00 PM Location: Old Main. I will be carrying an ACX meetup sign. Coordinates: 87G4Q4WP+HV Event link(s): LessWrong SAN JUAN, PUERTO RICO Contact: Dan Gelfarb, danielgelfarb[at]gmail[dot]com Time: Saturday, September 10, 1:00 PM Location: Lote 23, back corner under the tents. I will be wearing a blue shirt with a sign that says ACX meetup on it. Coordinates: 77CMCWVM+W32 Event link(s): LessWrong PROVIDENCE, RI Contact: James Bailey, feanor1600[at]gmail[dot]com Time: Saturday, September 17, 4:00 PM Location: Prospect Terrace park, to the right of the Roger Williams statue Coordinates: 87HCRHJV+24 Event link(s): LessWrong SIOUX FALLS, SD Contact: S. C., villainsplus[at]protonmail[dot]com Time: Sunday, October 2, 5:00 PM Location: 410 E 26th St, Sioux Falls, SD 57105 - the pavillion on the west side of McKennan Park, or the tables just south of it if I can't book it. I'll be the guy with the grill. Coordinates: 86M5G7JH+W57 Event link(s): LessWrong MEMPHIS, TN Contact: Michael, michael[at]postlibertarian[dot]com Time: Monday, September 5, 1:00 PM Location: French Truck Coffee at Crosstown Concourse, Central Atrium 1350 Concourse Ave, Memphis, TN 38104. We will be at one of the many tables near French Truck Coffee and I will have a sign that says ACX MEETUP. Coordinates: 867F5X2P+QHC Event link(s): LessWrong Group info: We meet about every month or so. We've been around since 2019 but only regularly since mid 2021 due to the pandemic. We have a Discord server. NASHVILLE, TN Contact: Ellen, enwiegand[at]gmail[dot]com Time: Saturday, October 1, 11:00 AM Location: OneCity Nashville (8 City Blvd, Nashville, TN 37209), next to the volleyball courts. I'll have a pink ballcap that says SPINSTER on it. Coordinates: 868M552H+XW Event link(s): LessWrong AUSTIN, TX Contact: Silas Barta, sbarta[at]gmail[dot]com Time: Saturday, October 8, 12:00 PM Location: 4001 N Lamar, Austin Texas, park by Central Market near stone tables and tents Coordinates: 86248746+8C Event link(s): LessWrong Group info: Austin LessWrong has a weekly focused discussion, a weekly social mixer, a weekly online book club, and a monthly movie night. Been around since 2011. Notes: Location may change as we are talking to other venues BRYAN/COLLEGE STATION, TX Contact: Kenny, easwaran[at]gmail[dot]com Time: Friday, September 9, 5:00 PM Location: Back patio of Torchy's Tacos at Texas and New Main. I'll have a yellow umbrella and pinkish/purple hair Coordinates: JMFC+4J Event link(s): LessWrong DALLAS, TX Contact: Ethan Morse, ethan[dot]morse97[at]gmail[dot]com, Discord: ethanmorse#5255 Time: Sunday, September 11, 12:00 PM Location: Union, 3705 Cedar Springs Rd, Dallas, TX 75219. We'll be in the upstairs conference room. Coordinates: 8645R55R+9M9 Event link(s): LessWrong Notes: Please RSVP on LessWrong so I know how much food to get HOUSTON, TX Contact: Eric Magro, eric135033[at]gmail[dot]com Time: Sunday, September 18, 4:00 PM Location: Empire Cafe, 1732 Westheimer Rd, Houston, TX 77098 ---- Look for a table with an ACX MEETUP sign. Coordinates: 76X6PHVW+5H Event link(s): LessWrong Group info: There are meetups every week. We have a Discord and a Facebook group. WACO, TX Contact: Mike, BaylorACX[at]gmail[dot]com Time: Saturday, October 1, 1:00 PM Location: Cameron Park, picnic tables next to Jacob's Ladder Coordinates: 8634HVG2+V9 Event link(s): LessWrong Notes: Please email me if you're thinking about attending! Would love to start an ACX community here :) SALT LAKE CITY, UT Contact: Ross Richey (aka Jeremiah), wearenotsaved[at]gmail[dot]com Time: Saturday, October 8, 3:00 PM Location: Liberty Park near the ChargePoint stations Coordinates: 85GCP4WF+VJ Event link(s): LessWrong Group info: We meet every other month, we do book clubs and movie nights as well. Notes: Will be outdoors. If the weather looks bad, email event organizer to check on location. CHARLOTTESVILLE, VA Contact: RL, effectivealtruismatuva[at]gmail[dot]com Time: Sunday, September 4, 5:00 PM Location: 12 Rotunda Drive Charlottesville, VA 22903 - We’ll meet at the picnic tables across the street from The Virginian. There will be an ACX sign. Coordinates: 87C32FPX+3H4 Event link(s): LessWrong LYNCHBURG, VA Contact: Craig, craigbdaniel[at]gmail[dot]com Time: Saturday, September 17, 4:00 PM Location: Three Roads Brewing - I will be wearing a purple t-shirt and will place an ""ACX"" card on the table Coordinates: 8792CV65+5G NORFOLK, VA Contact: Willa, walambert[at]pm[dot]me Time: Sunday, September 18, 4:00 PM Location: Pagoda & Oriental Garden, 265 W Tazewell St, Norfolk, VA 23510. I will be wearing a bright green shirt, will have a large green & yellow hat on, and will have a sign with ACX Meetup on it. Coordinates: 8785RPX4+W3 Event link(s): LessWrong, Facebook event Group info: Hi! Virginia Rationalists was co-founded in Norfolk VA earlier this year by Willa & Yitzi with the goal of growing a thriving ACX / LW / EA community in our city & the state of Virginia. We meet every week at Fair Grounds cafe on Wednesday evenings from 5-7:30pm Eastern Time. We have a Discord server and a Twitter. RESTON, VA Contact: James, jrbalch333[at]gmail[dot]com Time: Saturday, September 24, 1:30 PM Location: The matchbox at 1900 Reston Station Blvd, Reston, VA 20190 on the 1st floor of the giant Google building. I'll be holding a copy of Sapiens. Coordinates: 87C4WMX6+9X Event link(s): LessWrong Notes: Email me to be added to the WhatsApp group RICHMOND, VA Contact: Cedar, cedar[dot]ren+acxmeetup[at]gmail[dot]com, @Cedar at this Discord server Time: Saturday, October 1, 2:30 PM Location: Richmond Public Libraries, West End Branch 5420 Patterson Ave, Richmond, VA 23226 Coordinates: 8794HFHQ+3G Event link(s): LessWrong Notes: Please RSVP on LessWrong & optionally reach out to me on Discord to introduce yourself! BURLINGTON, VT Contact: Forrest, lucidobservor[at]gmail[dot]com Time: Saturday, September 10, 2:00 PM Location: Battery Park, at the benches in the south-western corner of the park, near the cannons facing the lake. I will have an 'ACX Meetup' sign. Coordinates: 87P8FQJH+8P Event link(s): LessWrong BELLINGHAM, WA Contact: Alex, bellinghamrationalish[at]gmail[dot]com Time: Thursday, September 29, 5:30 PM Location: Lake Padden Park, at one of the tables near the lake by the dog park. If it's rainy, we'll meet in one of the two covered gazebo areas just north (right, if you're facing the lake) of the planned spot. If the forecast looks really bad (e.g. very cold), I'll post an indoor location to the Meetup.com page at least three days in advance. Coordinates: 84WVMHX3+GM Event link(s): LessWrong, Meetup.com Group info: Bellingham Rationalish discusses (in good faith!) topics in and around rationality. We usually meet the evening of the last Wednesday of each month. Our first meeting was a 2021 ACX Everywhere meetup. Notes: Please RSVP on Meetup so I have an idea how many people to expect. Kids, animals, food, beverages, etc. are all welcome. SEATTLE, WA Contact: Nikita Sokolsky, sokolx[at]gmail[dot]com Time: Sunday, October 9, 5:00 PM Location: Optimism Brewing (1158 Broadway, Seattle) Coordinates: 84VVJM7H+4Q Event link(s): LessWrong, Facebook event, Meetup.com Notes: Please RSVP on LessWrong (or FB/Meetup) for planning purposes MADISON, WI Contact: Mary Wang, mmwang[at]wisc[dot]edu Time: Saturday, September 10, 1:00 PM Location: 1022 High St. Blue house with red porches. If weather permits, we'll be in my large backyard, which has more seating now than last year. If rain, come in the side door. There will be air purifiers and open windows. Masks optional. Look for a sign at the end of the driveway that says ACX/SSC Meetup. Coordinates: 86MG3H3X+XW Event link(s): LessWrong, Facebook event Group info: We have met fortnightly in the past, but quit last year when it got too cold to meet outside. We typically have shared a meal, sat around my kitchen table and talked. Have held a Solstice celebration.

Inline links: 866MP88H+53, LessWrong, 8559FVVQ+6C, LessWrong, 849VGP8C+RRG, LessWrong, here, 849VVP5R+X7V, LessWrong, mailing list, Discord server, Facebook group, 856393VX+VQ, LessWrong, 84FW6W8H+C5, LessWrong, 8554M526+7H, LessWrong, the server, 8553XHWM+GP, LessWrong, LessWrong group, website, 8554J48R+WCX, LessWrong, Facebook event, 8544PVQ8+Q7, LessWrong, Meetup.com, Discord server, 849VQHC3+V8, LessWrong, 849W825J+6P, LessWrong, 85544VW4+RV, LessWrong, 85GP2V96+JQ, LessWrong, 85FJ9QXP+QMF, LessWrong, 85FQP2VP+9R, LessWrong, 85FPMW64+MW, LessWrong, Meetup.com, Facebook group, 87H84PCH+CM, LessWrong, 87H9QFFH+J7, LessWrong, 87H9836C+8VG, LessWrong, 87C4WX33+3J, LessWrong, Facebook event, 76RWH224+44, LessWrong, 862J9RCF+G6, LessWrong, 76QXRR65+V2, LessWrong, Facebook group, Discord server, Meetup.com group, 76WWJQ2X+82, LessWrong, Discord link, 862QCPR3+PX, LessWrong, 865RXJ68+2W, LessWrong, 865QRH2F+V8, LessWrong, Meetup.com, 73H475M3+JP, LessWrong, Meetup.com, our website, 85M5JQ6P+96, LessWrong, 86GH4Q7G+H8F, LessWrong, Discord server, 86HJV9FH+84, LessWrong, Chicago Rationality, 86JJ28X9+5WQ, LessWrong, 86FM4FX6+4Q, LessWrong, our Discord, 86GMC3GG+728, LessWrong, 86CQ3F4X+VF, LessWrong, 76XFXX73+8R, LessWrong, Website, 87JC9W3M+PR, LessWrong, Facebook event, Mailing list, Facebook group, Meetup.com, here, 87J9899F+H7H, LessWrong, Facebook event, Discord, 87F5774P+53, LessWrong, 86JR9WG9+R6, LessWrong, 86P8WPRW+76, LessWrong, 86F72CM8+RR, LessWrong, Meetup.com, 86CFJP4R+XV, LessWrong, 868CP4HW+CV, LessWrong, 8773X4Q3+QW, LessWrong, a Discord, LessWrong, 87G7QGW9+RJ, LessWrong, 87G7982Q+2CP, LessWrong, 85864RHJ+3H, LessWrong, Facebook event, Discord server, 85F2G46W+FG, LessWrong, 87J3W467+8P, 87G8VJRW+99, LessWrong, 87G7PX9M+4J3, LessWrong, Discord, Google Group, Perkins Restaurant & Bakery, 87H7GWCH+GF, LessWrong, 87M46FM6+Q5P, LessWrong, 86HWG96Q+GC5, LessWrong, Clinton Shelter, 86FVX3C3+QF, LessWrong, 86HRMCCV+9R, LessWrong, 8674MG3C+MW, LessWrong, 84PRJWR7+XC6, LessWrong, 84PRHP5P+VQ, LessWrong, 84PR2WX4+VV, LessWrong, 84QVG8FG+V4, LessWrong, Meetup.com, Meetup.com, 87G562QQ+8P, LessWrong, on LessWrong, 87G2JRFX+48, LessWrong, 87F6WRXG+FQ, LessWrong, Discord, Google Calendar, Facebook, Meetup, Google Group, 87G2C3Q4+773, LessWrong, 87G4Q4WP+HV, LessWrong, 77CMCWVM+W32, LessWrong, 87HCRHJV+24, LessWrong, 86M5G7JH+W57, LessWrong, 867F5X2P+QHC, LessWrong, Discord server, 868M552H+XW, LessWrong, 86248746+8C, LessWrong, Austin LessWrong, JMFC+4J, LessWrong, 8645R55R+9M9, LessWrong, 76X6PHVW+5H, LessWrong, Discord, Facebook group, 8634HVG2+V9, LessWrong, 85GCP4WF+VJ, LessWrong, 87C32FPX+3H4, LessWrong, 8792CV65+5G, 8785RPX4+W3, LessWrong, Facebook event, Discord server, Twitter, 87C4WMX6+9X, LessWrong, this Discord server, 8794HFHQ+3G, LessWrong, 87P8FQJH+8P, LessWrong, 84WVMHX3+GM, LessWrong, Meetup.com, 84VVJM7H+4Q, LessWrong, Facebook event, Meetup.com, 86MG3H3X+XW, LessWrong, Facebook event

Highlights From The Comments On Billionaire Replaceability

September 22, 2022 · Original source

I thought a bit about credit allocation (mostly from an effective altruism point of view).

I think the political power of billionaires is vastly overestimated. I’ve talked before about how there’s very little money in politics because spending money on politics doesn’t work. Since then I think the case has gotten even stronger. Michael Bloomberg sunk in the 2020 primary despite having $50 billion dollars. And effective altruism tried to use $10 million of Sam Bankman-Fried’s money to get a biosecurity expert elected to Congress in Oregon. They were pretty smart about it: chose a district with no incumbent, found a really amazing candidate with an incredible personal backstory, pulled out all the stops. They spent the third most of any race in the country - about as much as it was possible to spend, I don’t know what else you could even spend the money on - and they lost by a landslide in the primary.

Inline links: talked before about how there’s very little money in politics because spending money on politics doesn’t work.

Spring Meetups Everywhere 2023

April 10, 2023 · Original source

No direct inline source block was recovered for this mention.

Your Book Review: Lying for Money

May 26, 2023 · Original source

SBF went to considerable time and expense to signal Effective Altruist group affiliation: in 2022, the FTX Future Fund gave more than $160 million to EA causes. In April 2022, he appeared as a guest on the 80,000 Hours podcast for a 3-hour interview with Rob Wiblin.

Inline links: FTX Future Fund gave more than $160 million to EA causes

While I won't enter a discussion of whether Effective Altruism is a "religion," the EA community does seem to share some common traits with religious congregations. When someone is part of your congregation, they're not just signaling shared group affinity; it's specifically the sort of group where membership also signals moral virtue. (If you're an Effective Altruist, you probably trust a fellow EA more than you trust a fellow rock climber, or a fellow Trekkie.)

Meetups Everywhere 2023: Times & Places

August 25, 2023 · Original source

WELLINGTON, NEW ZEALAND Contact: Ben W Contact Info: benwve[at]gmail[dot]com Time: Tuesday, October 3rd, 5:30 PM Location: Room MZ02 (on the mezannine floor), Rutherford House, 33 Bunny Street, Wellington 6011 Coordinates: https://plus.codes/4VCPPQCH+CMR Group Link: facebook.com/EffectiveAltruismWellington Notes: This meetup will be run in collaboration with Effective Altruism Wellington. The external door closes at 6pm, but if you call me I can let you in. reach me on 0+2+7+3+4+4+1+0+8+2

Inline links: https://plus.codes/4VCPPQCH+CMR, facebook.com/EffectiveAltruismWellington

EINDHOVEN, NETHERLANDS Contact: Jelle Contact Info: jelledonderz[at]gmail[dot]com Time: Saturday, Octover 21st, 3:00 PM Location: Strijp-S feelgood market grass field. Look for a printed sign that says 'ACX' Coordinates: https://plus.codes/9F37CFW5+X2 Group Link: https://www.eaeindhoven.nl/ Notes: Effective Altruism Eindhoven has biweekly meetups in the Hubble cafe on the TU/e campus. Rationality-themed conversations are welcome! https://www.eaeindhoven.nl/calendar

Inline links: https://plus.codes/9F37CFW5+X2, https://www.eaeindhoven.nl/

NEWTON, MASSACHUSETTS, USA Contact: duck_master Contact Info: duckmaster0[at]protonmail[dot]com Time: Saturday, September 9th, 12:00 PM Location: Newton Centre Green at 1221 Centre St, Newton, MA, USA Coordinates: https://plus.codes/87JC8RJ4+76 Event Link: https://www.lesswrong.com/events/fMcxBfAimukmqpAzB/2023-acx-meetups-everywhere-newton-ma Notes: If I run this it'll be totally open-ended (I'm planning ~12pm to ~2pm, but can totally go to any time). Also open beyond the rat community proper (I'll welcome postrats, alignment researchers, predictors, effective altruists, and rationalists).

Inline links: https://plus.codes/87JC8RJ4+76, https://www.lesswrong.com/events/fMcxBfAimukmqpAzB/2023-acx-meetups-everywhere-newton-ma

Highlights From The Comments On Kidney Donation

November 07, 2023 · Original source

The gut reaction you have to something like this depends a lot on your past experiences, how much you trust the author, your exposure to Effective Altruism, and how often you've had people try to pull one over on you at your expense. These all feed into your personality, heuristics, and priors. That's why you get reactions ranging from "Nope, you're a crazy liar" to "Interesting, tell me more".

I hate lying and am against it. I’m aware that I’m a media public intellectual type person, which means I have a higher-than-usual duty not to lie. And I’m involved with effective altruism, which everyone seems to constantly suspect of lying, and I try to fight that reputation by being scrupulously honest and recommending others do the same. I hate ever recommending lying. But I also can’t in good conscience recommend telling the truth to these people. They seem to have totally disqualified themselves as decent citizens who deserve the benefits of the social contract. I do psych evals for surgery sometimes, and I’ve read the papers on how to do them, and the official criteria all seem pretty reasonable, so I have no idea where these people are getting this from or, how they possibly go so wrong. Still, transplant evaluation psychiatrists are now right there alongside Gestapo officers at your door on my very very short list of people who it seems probably ethical to lie to. I don’t know how it came to this (I assume it involves lawyers and bioethicists somehow) but it doesn’t seem satisfactory.

Leaders can be described as getting people to do good stuff they should do anyway. Personally, I always tell people that when thry ask somebody for a favor, make it *AS EASY AS POSSIBLE* for that person to help you. The path to better more effective Altruism, and government as well, should keep those things in mind.

In Continued Defense Of Effective Altruism

November 28, 2023 · Original source

Search “effective altruism” on social media right now, and it’s pretty grim.

But the journalists think we’re a sinister conspiracy that has “taken over Washington” and have the whole Democratic Party in our pocket. Click to expand. Source: https://twitter.com/the_megabase/status/1728771254336036963 The only thing everyone agrees on is that the only two things EAs ever did were “endorse SBF” and “bungle the recent OpenAI corporate coup.”

Inline links: “taken over Washington”

And I do think the movement is worth fighting for. Here’s a short, very incomplete list of things effective altruism has accomplished in its ~10 years of existence. I’m counting it as an EA accomplishment if EA either provided the funding or did the work, further explanations in the footnotes. I’m also slightly conflating EA, rationalism, and AI doomerism rather than doing the hard work of teasing them apart:

Highlights From The Comments On Capitalism & Charity

January 11, 2024 · Original source

The Effective Altruist Forum now has a post on Economic Growth - Donation Suggestions And Ideas, listing suspected top charities for helping countries develop. These include ACX Grants winner Growth Teams, the Charter Cities Institute, GiveDirectly, and Overseas Development Institute.

Inline links: Economic Growth - Donation Suggestions And Ideas, Growth Teams, Charter Cities Institute, GiveDirectly, Overseas Development Institute

Spring Meetups Everywhere 2024

March 30, 2024 · Original source

BELGRADE Contact: Tanja Contact Info: tanja[dot]trninic[at]efektivnialtruizam[dot]rs Time: Sunday, April 7th, 2:00 PM Location: Venezelosova 20, Belgrade, Serbia. Effective Altruism Serbia is organizing a casual hang out + lunch in vegan and low-waste Kafe VeZa Coordinates: https://plus.codes/8GP2RFC9+36 Group Link: https://efektivnialtruizam.rs/ Notes: Please RSVP to tanja.trninic@efektivnialtruizam.rs so we can reserve enough tables for everyone.

Inline links: https://plus.codes/8GP2RFC9+36, https://efektivnialtruizam.rs/

Contra Stone On EA

May 30, 2024 · Original source

Lyman Stone wrote an article Why Effective Altruism Is Bad. You know the story by now, let’s start with the first argument:

Inline links: Why Effective Altruism Is Bad

Stone finds that Google Trends shows that searches for “effective altruism” concentrate most in the San Francisco Bay Area and Boston. So he’s going to see if those two cities have higher charitable giving than average, and use that as his metric of whether EAs give more to charity than other people.

He finds that SF and Boston do give more to charity than average, but not by much, and this trend has if anything decreased in the 2010 - present period when effective altruism was active. So, he concludes,

Highlights From The Comments On Nietzsche

August 08, 2024 · Original source

What I am proposing (and what makes my morality superior to both sides) is that good or evil should be judged completely independently of weakness or strength, using objective measurable criteria to determine who is deserving of help and who isn't. The reason rationalists with their "effective altruism" will never be a popular movement is because they do not DESERVE to be popular when they have no logical moral criteria to evaluate whom their altruism should prioritize. When your "effective altruism" saves the lives of 300 sub-saharan africans who then go on to murder gay people indiscriminately because their religion tells them to, or immigrate to Europe and rape and kill twelve year olds, YOU are personally responsible for the deaths they caused. Before you criticize OTHER people's morality, maybe you should consider subscribing to a moral philosophy that actually considers downstream effects, instead of treating the lives of evil people as being equally valuable to the lives of good people. Or do you not BELIEVE in the concept of good and evil?

It would be one thing if you could meaningfully ad baculum, but rationalists and Effective Altruists are substantially weaker than tribalists and ingroup preference enjoyers, so to anyone outside your bubble this tendency just comes off as impotent sneering.

Links For December 2024

December 17, 2024 · Original source

37: Rethink Priorities’ public polling on EA. Good example of the maxim “You wouldn't worry so much about what others think of you if you realized how seldom they do.” Approximately 1% of people have heard of effective altruism, and their opinion is mostly “I think it has something to do with charity, so I guess it sounds nice”. Median opinion on FTX and SBF was “never heard of them” (only 20% of people had!)

Inline links: Rethink Priorities’ public polling on EA

49: There’s been a Twitter spat over effective altruism. Back in 2019, Peter Singer published an article saying that rich donors gave $1 billion to rebuild Notre Dame after a fire, but that could have saved ~285,000 lives and maybe donors should take that equally seriously. This month, the NYT used “effective altruists are against restoring Notre Dame” as a jumping-off point for its real complaint (it would rather we have "a philanthropy network that gave specifically to social justice movements . . . racial justice groups, climate justice groups and transgender protection groups"). There were several good responses, most notably Dylan Matthews’.

Inline links: Dylan Matthews’

But I also think that, overall, this is a story of us taking the NYT’s bait (and hopefully learning not to do so in the future). The world really wants to believe that effective altruists are evil humorless people who want to prevent every kind of good except raw life-saving and think you’re a moral monster for not agreeing. One thing I’ve learned in my time as a blogger is that if the world wants to think something that much, they will seize on anything at all in your writing that even faintly suggests it, and so you can’t afford to be even slightly edgy or ambiguous, and really you should insert “BY THE WAY, I'M NOT SAYING THE HORRIBLE THING YOU’RE DESPERATE TO ATTRIBUTE TO ME” every other sentence as a reminder. Not every response did this, so a lot of people seized on this as EA admitting that we hate cathedrals and human flourishing and probably you personally.

Missing Heritability: Much More Than You Wanted To Know

June 26, 2025 · Original source

The failed candidate gene studies had sample sizes in the three or four digits. The new genome-wide studies needed five or six digits to even get started. It was prohibitively difficult for individual studies to gather so many subjects, genotype them, and test them for the outcome of interest, so work shifted to big centralized genome repositories - most of all the UK Biobank - and easy-to-measure traits. Among the easiest of all was educational attainment (EA), ie how far someone had gotten in school. Were they a high school dropout? A PhD? Somewhere in between? This correlated with all the spicy outcomes of interest people wanted to debate - IQ, wealth, social class - while being objective and easy to ask about on a survey.

Maybe there are genes we haven’t found yet For most of the 2010s, hypothesis 2 looked pretty good. Researchers gradually gathered bigger and bigger sample sizes, and found more and more of the missing heritability. A big 2018 study increased the predictive power of known genes from 2% to 10%. An even bigger 2022 study increased it to 14%, and current state of the art is around 17%. Seems like it was sample size after all! Once the samples get big enough we’ll reach 40% and finally close the gap, right? This post is the story of how that didn’t happen, of the people trying to rehabilitate the twin-studies-are-wrong hypothesis, and of the current status of the debate. Its most important influence/foil is Sasha Gusev, whose blog The Infintesimal introduced me to the new anti-hereditarian movement and got me to research it further, but it’s also inspired by Eric Turkheimer, Alex Young (not himself an anti-hereditarian, but his research helped ignite interest in this area), and Awais Aftab. (while I was working on this draft, the East Hunter Substack wrote a similar post. Theirs is good and I recommend it, but I think this one adds enough that I’m publishing anyway. You can see Gusev’s response to East Hunter here) In an interview with Aftab, Gusev explained his philosophy like so (I am excerpting heavily from a long interview and editing for flow/emphasis; completionists should read the whole thing): For teacher-reported ADHD, the twin heritability estimate was 69% while the GWAS-based heritability estimate [ie using genome-wide association studies where researchers actually try to find the genes involved] was just 5%; with similar gaps for other behavioral traits. These are huge differences! If we believe the twin study estimates, then this gap implies that there is a lot of causal genetic variation out there that GWAS/molecular data is not picking up. One way to think about this is that traits that are under stronger natural selection will have more of their genetic variants driven to low frequency, and thus less detectable by GWAS. So a big gap between GWAS and twins could imply that rare variants are very important due to strong selection. On the other hand, if we are skeptical of the twin study estimates, then this gap implies a substantial contribution from those environmental complexities I talked about previously. For a long time, the field of molecular genetics was operating under the assumption that the missing heritability was largely in the rare variants we had not yet measured. But a number of recent advances have started to tip the scales against that argument. First, some of the earlier molecular heritability estimates were found to be inflated by some mix of technical issues and cultural transmission, so the amount of missing heritability actually increased. Second, a new model was developed that could estimate total direct heritability using molecular data from mother-father-child trios, with very few model assumptions (the title literally states “… without environmental bias”; Young et al. 2018), and it too found estimates that were substantially lower than twins on average. Third, several studies have now actually measured the influence of rare variants in various forms, and they are so far not adding up to explain as much as we would expect from twin heritability estimates. Fourth, there is little evidence of the strong natural selection that would be needed to generate a massive trove of rare variants untagged by GWAS. I am a molecular geneticist, and this drumbeat of evidence from molecular data has convinced me that twin studies are either 2-3x inflated or estimate something fundamentally different from direct heritability. We’ll start by looking at Gusev’s first claim: that “earlier molecular estimates” (ie polygenic scores) are significantly inflated, or at least don’t mean what we thought they meant. This won’t be directly relevant to our question - even our original number of 17% implies missing heritability2, so moving it down a bit to 5-10% or up a bit to 20% doesn’t add or subtract from the fundamental mystery. But this discussion has gotten a lot of people extremely confused, and we’ll need to deconfuse ourselves if we’re going to get any further. Are Most Current Polygenic Scores Confounded? A polygenic score is one possible result of a genome-wide association study. These scores are algorithms which take a person’s genes as input and return information about their traits as output. Better polygenic scores can predict a higher percent of variance in a certain trait. For example, the latest polygenic score on educational attainment can predict up to 17% of the variance in how much schooling someone completes. Predictive power is different from causal efficacy. Consider a racist society where the government ensures that all white people get rich but all black people stay poor. In this society, the gene for lactose tolerance (which most white people have, but most black people lack) would do a great job predicting social class, but it wouldn’t cause social class3. It certainly wouldn’t be a “gene for social class” in the sense where it controls the part of your brain that helps you manage money, or where genetic engineering on this gene would make people richer. Here are three common ways that not-directly-causal genes can show up as predicting a trait: Population stratification: genes are linked to culture, and culture determines the trait, as in the racism-lactose example above. Many studies naturally mitigate this concern by using the UK Biobank of mostly white British samples, and by correcting for “principal components” that correspond to ancestry (and there are other, even more complicated ways to correct for this). But ancestry variation is fractal; no matter how uniform your sample, there will still be micro-differences you didn’t consider. For example, if you’re analyzing the educational attainment of white British people, it’s very relevant that families with Norman surnames still outperform their Saxon peers at Oxbridge admissions 900 years after William the Conqueror. If Britons with more Norman ancestry have non-education-related genes that their Saxon peers lack, these could be mistakenly classified as genes for education or other behavioral differences between the two groups. Assortative mating: Suppose that both height and wealth are desirable qualities in a mate. Then tall people will tend to marry rich people, and over generations, the same people will be both rich and tall. That means that even if wealth is 0% genetic, a study looking for “the gene for wealth” will be able to find genes that rich people have more often than poor people - namely, the genes for height. Or suppose that smart people tend to marry other smart people - surely true, if only because so many couples meet at college. Then all the intelligence genes will concentrate in the same people. So any study that tries to determine how much Intelligence Gene ABC affects intelligence will get inflated4 results, because everyone with Intelligence Gene ABC will also have many other intelligence genes - if the study naively asks “How much smarter are people with Gene ABC than people without it?”, it will find they are much smarter (because it’s accidentally including part of the effects of all the other intelligence genes that travel along with it). Parent-to-child transmission, aka “genetic nurture”: Children tend to share their parents’ genes. So if there’s a gene that causes parents to create a certain kind of childrearing environment, and that childrearing environment affects a trait, it will falsely look like a gene that directly causes the trait. Suppose Gene XYZ causes parents to read more books to their children, and reading books to children increases their IQ. Parents with Gene XYZ will tend to read books, so their kids will get high IQ. Those kids will also (probably) inherit Gene XYZ from their parents. So people with Gene XYZ will tend to have higher IQ. If you naively study which genes increase IQ, you’ll see Gene XYZ in more smart people than dumb people, and think it’s a “gene for IQ”. This is “causal” in a certain sense, but it’s not the one we traditionally think about, and it behaves importantly differently - for example, if you genetically engineer someone to have Gene XYZ, their IQ won’t go up (although their kids’ IQs might). How can we tell if a polygenic predictor is “direct” vs. confounded by these non-causal pathways? The most common technique is within-family comparisons: do the traditional “check if people with the gene differ on a trait from people without the gene” study, but limit its focus to (for example) sibling pairs. Suppose a couple has two children; the first child inherits Gene ABC and the second one doesn’t. If the first child is smarter than the second child, that provides some infinitesimal evidence that Gene ABC is a gene for intelligence. Repeat this process over hundreds of thousands of sibling pairs, and the infinitesimal evidence can reach statistical significance. Since the family unit is a perfect natural experiment that isolates the variable of interest (genes) while holding everything else (culture and parenting) constant, within-family results are protected against stratification, assortative mating, and genetic nurture effects. The culmination of this research program is Tan et al 2024, which finds that many polygenic predictors lose significant accuracy when retested among siblings. For example, educational attainment is 50% uncorrelated with direct genetic effects. You need to square this to figure out what percent is causal; when you do that, you find that the polygenic score that explained 14% of EA is only 4%pp direct genes, with the other 10%pp being nondirect5 confounders. So yes, it seems like most polygenic scores that don’t validate within families are confounded. However unhappy we previously were that we had only found 14% of genes for EA (vs. 40% expected), we should now be much more unhappy - we really only know 4% of genes that directly cause EA. On the other hand, you might say - so before we only knew 14%pp out of 40%. Now we only know 4%pp out of 40%. This is discouraging, but it doesn’t fundamentally change what we know about nature vs. nurture. Both 4%pp and 14%pp are less than 40% - with either number, we must be missing something or doing something wrong. Probably that’s insufficient sample size. We’ll keep working on sample size and other things, and eventually scrounge up the missing 26%pp or 36%pp or whatever of the variance, so this doesn’t change anything. All it means is that one predictive method that the average person never knew about in the first place doesn’t work as well as we thought. Who cares? Not doctors. So far this research has only just barely begun to reach the clinic. But also, all doctors want to do is predict things (like heart attack risk). They don’t care if they use causal vs. nondirect genes. It doesn’t matter if you’re “only” at higher risk of heart attack because you’re black, or Norman, or because your parents read books to you - you still need more heart attack medication! Polygenic embryo selection companies should care. They offer polygenic scores that can be used to select healthier or smarter embryos. If the predictors they use rely partly on variants that aren’t causal within families, their real benefits could be far lower than advertised. I talked to one of these companies, who said they’d already adjusted for these effects and expected their competitors had too - the proper antidote to this problem, sibling controls, is a natural choice when you’re literally picking between siblings. The biggest losers are the epidemiologists. They had started using polygenic predictors as a novel randomization method; suppose, for example, you wanted to study whether smoking causes Alzheimers. If you just checked how many smokers vs. nonsmokers got Alzheimers, your result would be vulnerable to bias; maybe poor people smoke more and get more Alzheimers. But (they hoped) you might be able to check whether people with the genes for smoking get more Alzheimers. Poverty can’t make you have more or fewer genes! This was a neat idea, but if the polygenic predictors are wrong about which genes cause smoking and what effect size they have, then the less careful among these results will need to be re-examined. But the reason I spent so much time on the subject here is that this has confused a lot of people into thinking heritability itself was confounded and is actually just 4%. When I read my first few blog posts on these findings, I came away thinking they were claiming to have discredited twin studies and heritability. And although I take partial ownership of my own poor reading comprehension, I maintain that the way that the new anti-hereditarians discuss this is pretty bad. For example, Turkheimer’s treatment of the Tan study above is called Is Tan Et Al The End Of Social Science Genomics?, and includes passages like: The median [direct genomic effect] heritability for behavioral phenotypes is .048. Let that sink in for a second. How different would the modern history of behavior genetics be if back in the 80s one study after another had shown that the heritability of behavior was around .05? When Arthur Jensen wrote about IQ, he usually used a figure of .8 for the heritability of intelligence. I know that the relationship between twin heritabilities and SNP heritabilities is complicated, and in fact the DGE heritability of ability is one of the higher ones, at .2336. But still, it seems to me that the appropriate conclusion from these results is that among people who don’t have an identical twin, genomic information is a statistically non-zero but all in all relatively minor contributor to behavioral differences. And comments included things like: I don’t know if [this study] is the end of social science genomics, but it should certainly be the end of attributing significant genetic influence to behavioral traits (despite the recent scientist-generated cartoons touting genes for “income”). And: There's no doubt that this reported findings have dealt a fatal blow to my conviction that behavioral traits are pre-eminently heritable…This is a remarkable example of an objective statistical fact mercilessly crushing the more subjective experiential sense of "A looks and acts more like B than C because A and B have the same parents." This subjective evidence is almost unshakable and universal in its application as a tried and tested psychosocial heuristic. And yet, here we are. Turkheimer is either misstating the relationship between polygenic scores and narrow-sense heritability, or at least egging on some very confused people who are doing that, and the dynamic was bad enough that I got confused myself for a while. But even more confusing, the new anti-hereditarians actually are saying that lots of behavioral traits have very low heritability! But this point requires different arguments, only tangentially related to these. So let’s move on to… Is Heritability Genuinely Low? (Part 1: GWAS & GREML) In the mid 2010s, when genome-wide association studies (GWAS) based polygenic predictors were getting better every year, it was easy to hope they might reach 40% and close the “missing heritability”. But since then, progress has stalled. The second-to-last tripling of sample size, from 300K to 1M between 2016 - 2018, increased predictive power from 6% → 12%. The last tripling, from 1M to 3M between 2018 - 2022, only increased predictive power from 12% → 14%. If you graph sample size vs. predictive power, it looks like there's an asymptote between 15 - 20% or so. (of which - remember - only 5% is directly causal!) Worse, a mid-2010s technique called GREML allowed researchers to estimate the percent of variance in a trait that comes from the sorts of common genes studied in GWAS, without having to identify the genes involved. A 2016 GREML paper suggested that the maximum share of variance that GWASs of educational attainment could ever discover was about 21% (again, compared to 40% predicted genetic from twin studies). Since unavoidable methodological issues will prevent GWASs from reaching the literal maximum possible, this agrees with the evidence suggesting an asymptote between 15 - 20%. So either twin studies are wrong and traits are less heritable than believed, or the heritability must lie somewhere other than the common genes identifiable by GWAS. What about rare genes? GWASs focus on genetic variation common enough to be worth including in a basic genetic test. Most of this is single nucleotide polymorphisms (“SNPs”). A single nucleotide is one letter of DNA - for example, a C or a G. Polymorphisms are genes that commonly vary in humans - sometimes across races (for example, some humans have a gene for light skin, and other humans have a gene for dark skin), and other times within races (for example, some white people have a gene that makes cilantro taste like soap, and others don’t). So SNPs are single-letter spots in DNA where different people often have different letters. How often? Some people say 1%, but the more practical definition is “often enough that someone has noticed and added it to the test panel”. There are three billion letters in the genome, of which only a few million are commonly-tested SNPs. But these SNP studies have limited7 ability to measure personal mutations and rare variants. Sometimes your parents’ egg and sperm cells mess up copying a nucleotide of DNA, and you get a mutation that isn’t inherited from your ethnic group or even from your subgroup/family line - it’s just some idiosyncratic DNA change that you might be the first person in history to have. Since scientists have never seen this mutation before, they don’t know about it and can’t test for it without doing something more expensive than a simple SNP screen. And SNP studies have limited ability to detect anything more complicated than a single letter changing to another single letter. But some mutations are more complicated structural variants. For example, some bits of DNA get stuck on repeat - one person might have GATGAT, another person might have GATGATGATGAT, and a third person might have fifty GATs in a row. Other bits come out backwards. Sometimes a whole chunk of DNA goes missing, or moves to the wrong place. Occasionally a gene reads The Selfish Gene by Richard Dawkins, takes it too seriously, and evolves some ridiculous trick for spamming itself all over the genome. So if even the best molecular studies seem to be asymptoting around 15-20% of variance in educational attainment, but twin studies suggest it’s 40% genetic, might rare variants and structural variants make up the missing 20-25%pp? This remains a topic of bitter disagreement. On the one side, hereditarians bring up a Darwinian argument: imagine a genetic engineer who hopes to find the genes for educational attainment and edit them to make everyone smart and successful. She looks harder and harder, becoming more and more exasperated as they fail to materialize. Finally, she realizes she’s been scooped: evolution has been working on the same project, and has a 100,000 year head start. In the context of intense, recent selection for intelligence, we should expect evolution to have already found (and eliminated) the most straightforward, easy-to-find genes for low intelligence. Therefore, everything left should be convoluted or hidden or impossible to work with. So although this requires a sort of god-of-the-gaps argument - where we keep pushing heritability into whatever genes are too weird for existing techniques to detect - there are some reasons to think God really is in the gaps here. And a 2017 paper uses some clever techniques to estimate the share of intelligence variation lurking in hard-to-measure genes and finds it’s more than half: “By capturing these additional genetic effects, our models closely approximate the heritability estimates from twin studies for intelligence and education.” (see also Wainschtein 2022, Sidorenko 2024) The anti-hereditarians disagree. They cite papers like Zeng which measure the strength of selection on intelligence and suggest that it’s too weak to concentrate so much of the variation in rare genes8. And Sasha Gusev mentions Weiner 2023, which finds that in fact rare variants “explain 1.3% (SE = 0.03%) of phenotypic variance on average – much less than common variants” (other experts say that burden heritability only captures some rare variants and is not the right tool for this problem). But it may not even matter, because another set of findings suggests that heritability is genuinely low even when the rare variants are counted. Is Heritability Genuinely Low? (Part 2: Sib-Regression and RDR) Two newer methods, Sib-Regression and RDR, ask: using what we know from genetic studies, how much genetic variation do we think exists, total, across both common and rare genes? On average siblings share 50% of genes. But there’s a little randomness in meiosis, so some siblings might share 40% and others might share 60%. The more genetic influence on a trait, the more similar sibling pairs who share 60% of their genes will be, compared to sibling pairs who only share 40% of their genes. Since 60%-gene siblings and 40%-gene siblings are both equally part of the same family, you can use these numbers to calculate heritability unconfounded by a range of family factors. This is Sib-Regression. If you do a more complicated statistical process to extend the same idea to relatives other than siblings, it’s relatedness disequilibrium regression or RDR. GWAS asks: Looking at common easy-to-study genes, how much variation in a trait have we explained right now? GREML asks: looking at common easy-to-study genes, how much variation could we ever explain? But sib-regression and RDR ask a question more like twin studies: considering all genes, whether common / rare / easy-to-study / hard-to-study, how much variation is there total? This could address the rare variant objection mentioned above. And in many ways, these techniques are better than twin studies - Sib-Regression eliminates many potential biases, and RDR eliminates even more (although it’s harder to pull off, requiring more genetic information and computational resources). These techniques are new and hard-to-use, and only a few published studies have applied them to the sorts of behavioral traits we’re interested in: Young et al (2018) did Sib-Regression and RDR to genetic data from Iceland. Sib-regression found educational attainment = 40% (±15%) heritable, and RDR found 17% (±9%) heritable. Kemper et al (2021) did Sib-Regression only to genetic data from Britain. It found educational attainment = 14% heritable. This number conflicts with the 40% from the Young paper. Why? Unclear, but it could be selection bias - Young’s Icelandic sample was representative of the country; Kemper’s British population were Biobank volunteers who tend tend to be healthier and higher-class than the population at large. Upper-class people may have restricted range in educational attainment, or different factors affecting their educational attainment compared to the overall population. Either way, these are closer to the low estimates from GWAS and GREML (7% direct, 20% total), than to the higher estimates from twin studies (40%, generally presumed direct). And we can no longer use contributions from rare variants to paper over the difference. So what is going on? It seems like we have to accept one of three possibilities: Either something is wrong with twin studies. Or something is wrong with Sib-Regression and RDR (and then we can explain away GWAS and GREML by saying they’re missing rare variants). Or something is wrong with how we’re thinking about this topic and comparing things. What’s Going On? (Part 1: Is Something Wrong With Twin Studies?) Twin studies have dominated discussion of behavioral genetics for decades, so there’s a vast literature investigating their various assumptions and whether something might be wrong with them. Here are some of the assumptions and what the research says about each. Some of these will be duplicates of the GWAS confounders above, but we’ll go through them again anyway to review how they apply to twins. 1: Parents Treat Fraternal And Identical Twins The Same: Twin studies claim that twins are a uniquely powerful genetic laboratory; both fraternal and identical twin pairs have equally concordant environments, but identical twins have more concordant genes. Therefore, the more similar identical twin pairs are relative to fraternal twin pairs, the more heritable a trait must be. But this conclusion falls apart if identical twin pairs actually have more similar environments than fraternal twin pairs do, maybe because parents (knowing their twins are identical) treat them more similarly than they would fraternal twins. Would-be twin-study-discreditors have been trying to argue that this must be true for decades, but it’s always been a kind of quixotic battle. Remember, twin studies find many behavioral traits like IQ are >60% heritable, so you would need to prove not only that parents treat identical twin pairs differently from fraternal, but that this was an overwhelming effect. Parents of identical twins would have to obsessively expose them to the exact same stimuli in the exact same order; parents of fraternal twins would have to send one to the Gifted Advanced Placement Acceleration program while locking the other in a box and force-feeding them lead pellets. Common sense tells us there are no such differences, and studies confirm this: when parents are wrong about their twins’ status (eg they have fraternal twins, but falsely think they’re identical, or vice versa) their trait similarity matches their real status, rather than the incorrect status that determined how their parents treat them; parental treatment explains less than 1% of why identical twin pairs are more concordant (2, 3, 4). See also Felson 2013, which tries to measure environmental similarity and adjust for it, with minimal effects. Are these two cuties monozygotic or dizygotic? Are you sure? (answer) 2: Fraternal And Identical Twins Have Equally Concordant Uterine Environments: Fraternal twins have different sacs in the uterus and use different placentas. Most identical twins share a placenta, and some share an amniotic sac. If trait similarity is caused by sharing a placenta or sac (maybe because the placenta is defective, the fetal brain is starved of nutrients, and so the person has a lower IQ when they grow up), twin studies would falsely read this identical-fraternal difference as genetic. Luckily this is easy to study; not all identical twins share a placenta or sac, so you can cleanly separate the effect of uterine environment from genetics. If you measure enough traits, you can find small deviations in some, but it’s not clear whether this is just multiple testing, and in any case the deviations are small. The best studies suggest this chips off somewhere between 0 - 3% from heritability estimates9. 3: There is little assortative mating: We discussed this one above in the earlier section on GWAS - smart/pretty/kind/whatever people tend to marry other smart/pretty/kind/whatever people. Why would this bias twin study results? Identical twins share 100% of their genes. Fraternal twins ought to share 50% of their genes - but they get half their genes from their mother, and half from their father. In the degenerate case where the mother and father have exactly the same genes (“would you have sex with your clone?”) even fraternal twins will be extremely similar (although not quite identical, since they’ll get different alleles from each clone). In the more plausible case where mothers and fathers are just a little more alike than chance (eg because smart people tend to marry other smart people), fraternal twins will share a genetic tendency towards a trait somewhat more than their 50% shared genes suggest. Since this makes fraternal twin pairs more (genetically) like identical twin pairs, and twin studies assess heritability as the difference in fraternal-identical-twin-pair concordance, this bias would make twin studies underestimate heritability. But this is the opposite of what you would need to “discredit” twin studies - if this bias is true, then everything is more genetic than twin studies think. And unlike the previous two biases, this one seems real and important, so much so that when you adjust for it, the heritability of educational attainment rises from ~40% to ~50%. I’m only mentioning this one here because some anti-hereditarians argue that you can’t trust twin studies because of assortative mating, without mentioning that this can only bias them down. 4: Population stratification: This is often large and worth worrying about, but it applies to identical and fraternal twin pairs equally, and doesn’t bias twin study heritability estimates much (though it might shift the balance between shared and non-shared environment). See eg the sentence around footnote 30 here. 5: Non-additive / “interaction” effects: These are theoretically interesting, but all research thus far has found they are minimal (1, 2). Some experts think this may miss rarer or harder-to-find interactions; we’ll return to this later. 6: “Genetic nurture”, parent-to-child Mentioned above: if there is a gene for reading books to kids, and reading books raises IQ, it will look like a “gene for IQ”. This isn’t as relevant to twin study estimates of heritability, since both identical twins and fraternal twins are equally related to their parents, and any trait caused by genetic nurture wouldn’t differ between them (and therefore would not falsely appear heritable in this design). Rather, they would appear as shared environment. 7: “Genetic nurture”, sibling-to-sibling That is, suppose your sibling’s traits influence your own development. For example, suppose your sibling has a gene that makes them sabotage your schoolwork, causing you to fail and drop out of school early. An identical twin would share this gene with their sibling more often than a fraternal twin, making it look like a “gene for doing badly at school” (since the people who have it do worse at school than those who don’t). Why are we even talking about this? Do we really think it’s a big part of the variance in behavioral traits? Challenging twin study heritability estimates through this route requires inhabiting a weird no-man’s-land where otherwise-invisible genetic and environmental pathways suddenly flare up when you say the magic words “it was done by a sibling”. For example, this requires a strong effect of shared environment - that is, your educational attainment has to depend on whether you’re being sabotaged or not. But in general, shared environmental effects are weak. And it requires a strong effect of genes - that is, this mechanism only works if your sibling’s tendency to sabotage you is highly genetically determined. But we’re deploying this claim to deny that traits like IQ or educational attainment are highly genetically determined. So to get much out of this, the tendency to sabotage siblings would have to be more genetic than other behavioral traits! The reason this convoluted possibility gets brought up so often is that, unlike the more plausible parent-to-child genetic nurture, twin studies can’t rule it out. So if you really want to deny twin studies, this is one of your best bets. But when investigated, this has effects indistinguishable from zero. I’ve been a bit mean in this whole section, because people really like to dismiss twin studies as “Oh, don’t you know, those depend on assumptions, I bet you never considered that assumptions might be wrong”, and then Gish Gallop you with different assumptions until you give up. But scientists have actually done a lot of really good work checking the assumptions and they mostly hold. An alternative way of validating twin studies (brought up by Noah Carl in this article) is to check them against their close cousins, adoption studies and pedigree studies. Pedigree studies investigate large family trees, and check how trait similarity decreases with genetic distance. They avoid twin specific biases (like different treatment of fraternal vs. identical twin pairs, or different prenatal environments), while adding others like assortative mating. Here are the heritabilities of IQ and EA found in pedigree studies10 (see footnote for sources and caveats, and see also here and here for somewhat similar designs): Adoption studies investigate whether adoptees’ traits are more correlated with their adoptive or biological parents. They avoid a large swathe of biases, at the risk of introducing new adoption-related biases of their own (like the possibility that agencies deliberately place adoptive children with parents who are culturally or behaviorally similar, or the possibility that adoptees were adopted late enough to still get some shared environment from their biological parents). Here are the findings of some of the largest and best11: Both straightforwardly confirmed the larger heritability numbers found in twin studies. I would add the evidence from some less formal “adoption studies”12. During residency, I spent a few months working in a child psychiatric hospital for the worst of the worst - kids who committed murder or rape or something before age 18. Many of these children had similar stories: they were taken from their parents just after birth because the parents were criminals/drug addicts/in jail/abusing them. Then they were adopted out to some extremely nice Christian family whose church told them that God wanted them to help poor little children in need. Then they promptly proceeded to commit crime / get addicted to drugs / go to jail / abuse people, all while those families’ biological children were goody-goodies who never got so much as a school detention. When I met with the families, they would always be surprised that things had gone so badly, insisting that they’d raised them exactly like their own son/daughter and taught them good Christian morals. I had to resist the urge to shove a pile of twin studies in their face. This has left me convinced that behavioral traits are highly heritable to a level that it would be hard for any study to contradict. Ultimate source here. Although the study is confusing about this, I think it’s trying to say that almost 90% of subjects were adopted before age 2. But I don’t think studies do contradict this. Given the degree to which their assumptions have been validated, and the level of confirmation from pedigree and adoption studies, I think they have earned a presumption of accuracy. Doubting the twin studies doesn’t seem like a promising route to reconciling the twin-vs-Sib-Regression/RDR discrepancy. What’s Going On? (Part 2: Is Something Wrong With Sib-Regression And RDR?) Sib-Regression is a clever way of avoiding most biases. Its independent variable - the degree to which some sibling pairs end up with slightly more shared genes than others - is even more random and exogenous than the difference between fraternal and identical twins. It can sometimes have biases related to assortative mating (which would falsely push heritability down), but otherwise it’s pretty good. RDR has many of the same advantages, and allows more diverse relationships and so larger sample sizes. It’s hard to think of ways these methods could be wildly off. There is one caveat: although RDR includes most of the rare and structural variants missed by GWAS, in theory it can miss certain ultra-rare variants which are so uncommon that they aren’t shared between some of the relative pairs used in RDR. De novo variants that occurred during the subject’s own conception would be in this category, if the subject didn’t have children or didn’t pass on that gene13. This seems like a pretty small subcategory of genetic variation, and I wouldn’t normally expect that much of importance to be hiding here, but maybe it’s more important than it seems. RDR also doesn’t include much variance caused by statistical interactions between genes. Although we said above that these are usually found to be insignificant, they might be more important in a trait like intelligence that has been under recent evolutionary selection that lops off easily-detectable sources of variance and leaves only the weird obscure ones behind. There’s limited ability for classical Mendelian dominance to affect common variants, but more complicated genetic interactions might still prove important. Overall these are strong methods, and their failure to converge is troubling. If forced to explain them away, we might tell a story like: So far, there is only one RDR study and a few Sib-Regression studies, so we should wait for more data before updating too hard.

Inline links: Sasha Gusev, The Infintesimal, Eric Turkheimer, Alex Young, Awais Aftab, wrote a similar post, here, read the whole thing, Young et al. 2018, 2, 3, families with Norman surnames still outperform their Saxon peers at Oxbridge admissions, or other behavioral differences between the two groups, 4, Tan et al 2024, https://substackcdn.com/image/fetch/$s_!ioe2!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F05c5bec7-469c-40d2-b908-68d8583c9cca_766x766.png, 5, Polygenic embryo selection, need, Is Tan Et Al The End Of Social Science Genomics?, 6, like, And, 300K, 1M, 3M, A 2016 GREML paper, 7, evolves some ridiculous trick, a Darwinian argument, a 2017 paper, Wainschtein 2022, Sidorenko 2024, Zeng, 8, Weiner 2023, other experts say, meiosis, Young et al (2018), Kemper et al (2021), their trait similarity, matches their real status, 2, 3, 4, Felson 2013, https://substackcdn.com/image/fetch/$s_!r3kV!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd575f2d6-3619-40e6-9a5e-f9f1ec1399a5_650x422.png, answer, The best studies, 9, seems real and important, here, 1, 2, when investigated, in this article, 10, here, here, https://substackcdn.com/image/fetch/$s_!b3LF!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc094f9c0-4c71-48cf-89dc-615498d94812_483x51.png, 11, https://substackcdn.com/image/fetch/$s_!XFWU!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F85f433e5-d141-47b7-8dc5-2271925032e9_483x102.png, 12, https://x.com/cremieuxrecueil/status/1935731422205010135, here, 13

For example, educational attainment is 50% uncorrelated with direct genetic effects. You need to square this to figure out what percent is causal; when you do that, you find that the polygenic score that explained 14% of EA is only 4%pp direct genes, with the other 10%pp being nondirect5 confounders. So yes, it seems like most polygenic scores that don’t validate within families are confounded. However unhappy we previously were that we had only found 14% of genes for EA (vs. 40% expected), we should now be much more unhappy - we really only know 4% of genes that directly cause EA. On the other hand, you might say - so before we only knew 14%pp out of 40%. Now we only know 4%pp out of 40%. This is discouraging, but it doesn’t fundamentally change what we know about nature vs. nurture. Both 4%pp and 14%pp are less than 40% - with either number, we must be missing something or doing something wrong. Probably that’s insufficient sample size. We’ll keep working on sample size and other things, and eventually scrounge up the missing 26%pp or 36%pp or whatever of the variance, so this doesn’t change anything. All it means is that one predictive method that the average person never knew about in the first place doesn’t work as well as we thought. Who cares? Not doctors. So far this research has only just barely begun to reach the clinic. But also, all doctors want to do is predict things (like heart attack risk). They don’t care if they use causal vs. nondirect genes. It doesn’t matter if you’re “only” at higher risk of heart attack because you’re black, or Norman, or because your parents read books to you - you still need more heart attack medication! Polygenic embryo selection companies should care. They offer polygenic scores that can be used to select healthier or smarter embryos. If the predictors they use rely partly on variants that aren’t causal within families, their real benefits could be far lower than advertised. I talked to one of these companies, who said they’d already adjusted for these effects and expected their competitors had too - the proper antidote to this problem, sibling controls, is a natural choice when you’re literally picking between siblings. The biggest losers are the epidemiologists. They had started using polygenic predictors as a novel randomization method; suppose, for example, you wanted to study whether smoking causes Alzheimers. If you just checked how many smokers vs. nonsmokers got Alzheimers, your result would be vulnerable to bias; maybe poor people smoke more and get more Alzheimers. But (they hoped) you might be able to check whether people with the genes for smoking get more Alzheimers. Poverty can’t make you have more or fewer genes! This was a neat idea, but if the polygenic predictors are wrong about which genes cause smoking and what effect size they have, then the less careful among these results will need to be re-examined. But the reason I spent so much time on the subject here is that this has confused a lot of people into thinking heritability itself was confounded and is actually just 4%. When I read my first few blog posts on these findings, I came away thinking they were claiming to have discredited twin studies and heritability. And although I take partial ownership of my own poor reading comprehension, I maintain that the way that the new anti-hereditarians discuss this is pretty bad. For example, Turkheimer’s treatment of the Tan study above is called Is Tan Et Al The End Of Social Science Genomics?, and includes passages like: The median [direct genomic effect] heritability for behavioral phenotypes is .048. Let that sink in for a second. How different would the modern history of behavior genetics be if back in the 80s one study after another had shown that the heritability of behavior was around .05? When Arthur Jensen wrote about IQ, he usually used a figure of .8 for the heritability of intelligence. I know that the relationship between twin heritabilities and SNP heritabilities is complicated, and in fact the DGE heritability of ability is one of the higher ones, at .2336. But still, it seems to me that the appropriate conclusion from these results is that among people who don’t have an identical twin, genomic information is a statistically non-zero but all in all relatively minor contributor to behavioral differences. And comments included things like: I don’t know if [this study] is the end of social science genomics, but it should certainly be the end of attributing significant genetic influence to behavioral traits (despite the recent scientist-generated cartoons touting genes for “income”). And: There's no doubt that this reported findings have dealt a fatal blow to my conviction that behavioral traits are pre-eminently heritable…This is a remarkable example of an objective statistical fact mercilessly crushing the more subjective experiential sense of "A looks and acts more like B than C because A and B have the same parents." This subjective evidence is almost unshakable and universal in its application as a tried and tested psychosocial heuristic. And yet, here we are. Turkheimer is either misstating the relationship between polygenic scores and narrow-sense heritability, or at least egging on some very confused people who are doing that, and the dynamic was bad enough that I got confused myself for a while. But even more confusing, the new anti-hereditarians actually are saying that lots of behavioral traits have very low heritability! But this point requires different arguments, only tangentially related to these. So let’s move on to… Is Heritability Genuinely Low? (Part 1: GWAS & GREML) In the mid 2010s, when genome-wide association studies (GWAS) based polygenic predictors were getting better every year, it was easy to hope they might reach 40% and close the “missing heritability”. But since then, progress has stalled. The second-to-last tripling of sample size, from 300K to 1M between 2016 - 2018, increased predictive power from 6% → 12%. The last tripling, from 1M to 3M between 2018 - 2022, only increased predictive power from 12% → 14%. If you graph sample size vs. predictive power, it looks like there's an asymptote between 15 - 20% or so. (of which - remember - only 5% is directly causal!) Worse, a mid-2010s technique called GREML allowed researchers to estimate the percent of variance in a trait that comes from the sorts of common genes studied in GWAS, without having to identify the genes involved. A 2016 GREML paper suggested that the maximum share of variance that GWASs of educational attainment could ever discover was about 21% (again, compared to 40% predicted genetic from twin studies). Since unavoidable methodological issues will prevent GWASs from reaching the literal maximum possible, this agrees with the evidence suggesting an asymptote between 15 - 20%. So either twin studies are wrong and traits are less heritable than believed, or the heritability must lie somewhere other than the common genes identifiable by GWAS. What about rare genes? GWASs focus on genetic variation common enough to be worth including in a basic genetic test. Most of this is single nucleotide polymorphisms (“SNPs”). A single nucleotide is one letter of DNA - for example, a C or a G. Polymorphisms are genes that commonly vary in humans - sometimes across races (for example, some humans have a gene for light skin, and other humans have a gene for dark skin), and other times within races (for example, some white people have a gene that makes cilantro taste like soap, and others don’t). So SNPs are single-letter spots in DNA where different people often have different letters. How often? Some people say 1%, but the more practical definition is “often enough that someone has noticed and added it to the test panel”. There are three billion letters in the genome, of which only a few million are commonly-tested SNPs. But these SNP studies have limited7 ability to measure personal mutations and rare variants. Sometimes your parents’ egg and sperm cells mess up copying a nucleotide of DNA, and you get a mutation that isn’t inherited from your ethnic group or even from your subgroup/family line - it’s just some idiosyncratic DNA change that you might be the first person in history to have. Since scientists have never seen this mutation before, they don’t know about it and can’t test for it without doing something more expensive than a simple SNP screen. And SNP studies have limited ability to detect anything more complicated than a single letter changing to another single letter. But some mutations are more complicated structural variants. For example, some bits of DNA get stuck on repeat - one person might have GATGAT, another person might have GATGATGATGAT, and a third person might have fifty GATs in a row. Other bits come out backwards. Sometimes a whole chunk of DNA goes missing, or moves to the wrong place. Occasionally a gene reads The Selfish Gene by Richard Dawkins, takes it too seriously, and evolves some ridiculous trick for spamming itself all over the genome. So if even the best molecular studies seem to be asymptoting around 15-20% of variance in educational attainment, but twin studies suggest it’s 40% genetic, might rare variants and structural variants make up the missing 20-25%pp? This remains a topic of bitter disagreement. On the one side, hereditarians bring up a Darwinian argument: imagine a genetic engineer who hopes to find the genes for educational attainment and edit them to make everyone smart and successful. She looks harder and harder, becoming more and more exasperated as they fail to materialize. Finally, she realizes she’s been scooped: evolution has been working on the same project, and has a 100,000 year head start. In the context of intense, recent selection for intelligence, we should expect evolution to have already found (and eliminated) the most straightforward, easy-to-find genes for low intelligence. Therefore, everything left should be convoluted or hidden or impossible to work with. So although this requires a sort of god-of-the-gaps argument - where we keep pushing heritability into whatever genes are too weird for existing techniques to detect - there are some reasons to think God really is in the gaps here. And a 2017 paper uses some clever techniques to estimate the share of intelligence variation lurking in hard-to-measure genes and finds it’s more than half: “By capturing these additional genetic effects, our models closely approximate the heritability estimates from twin studies for intelligence and education.” (see also Wainschtein 2022, Sidorenko 2024) The anti-hereditarians disagree. They cite papers like Zeng which measure the strength of selection on intelligence and suggest that it’s too weak to concentrate so much of the variation in rare genes8. And Sasha Gusev mentions Weiner 2023, which finds that in fact rare variants “explain 1.3% (SE = 0.03%) of phenotypic variance on average – much less than common variants” (other experts say that burden heritability only captures some rare variants and is not the right tool for this problem). But it may not even matter, because another set of findings suggests that heritability is genuinely low even when the rare variants are counted. Is Heritability Genuinely Low? (Part 2: Sib-Regression and RDR) Two newer methods, Sib-Regression and RDR, ask: using what we know from genetic studies, how much genetic variation do we think exists, total, across both common and rare genes? On average siblings share 50% of genes. But there’s a little randomness in meiosis, so some siblings might share 40% and others might share 60%. The more genetic influence on a trait, the more similar sibling pairs who share 60% of their genes will be, compared to sibling pairs who only share 40% of their genes. Since 60%-gene siblings and 40%-gene siblings are both equally part of the same family, you can use these numbers to calculate heritability unconfounded by a range of family factors. This is Sib-Regression. If you do a more complicated statistical process to extend the same idea to relatives other than siblings, it’s relatedness disequilibrium regression or RDR. GWAS asks: Looking at common easy-to-study genes, how much variation in a trait have we explained right now? GREML asks: looking at common easy-to-study genes, how much variation could we ever explain? But sib-regression and RDR ask a question more like twin studies: considering all genes, whether common / rare / easy-to-study / hard-to-study, how much variation is there total? This could address the rare variant objection mentioned above. And in many ways, these techniques are better than twin studies - Sib-Regression eliminates many potential biases, and RDR eliminates even more (although it’s harder to pull off, requiring more genetic information and computational resources). These techniques are new and hard-to-use, and only a few published studies have applied them to the sorts of behavioral traits we’re interested in: Young et al (2018) did Sib-Regression and RDR to genetic data from Iceland. Sib-regression found educational attainment = 40% (±15%) heritable, and RDR found 17% (±9%) heritable. Kemper et al (2021) did Sib-Regression only to genetic data from Britain. It found educational attainment = 14% heritable. This number conflicts with the 40% from the Young paper. Why? Unclear, but it could be selection bias - Young’s Icelandic sample was representative of the country; Kemper’s British population were Biobank volunteers who tend tend to be healthier and higher-class than the population at large. Upper-class people may have restricted range in educational attainment, or different factors affecting their educational attainment compared to the overall population. Either way, these are closer to the low estimates from GWAS and GREML (7% direct, 20% total), than to the higher estimates from twin studies (40%, generally presumed direct). And we can no longer use contributions from rare variants to paper over the difference. So what is going on? It seems like we have to accept one of three possibilities: Either something is wrong with twin studies. Or something is wrong with Sib-Regression and RDR (and then we can explain away GWAS and GREML by saying they’re missing rare variants). Or something is wrong with how we’re thinking about this topic and comparing things. What’s Going On? (Part 1: Is Something Wrong With Twin Studies?) Twin studies have dominated discussion of behavioral genetics for decades, so there’s a vast literature investigating their various assumptions and whether something might be wrong with them. Here are some of the assumptions and what the research says about each. Some of these will be duplicates of the GWAS confounders above, but we’ll go through them again anyway to review how they apply to twins. 1: Parents Treat Fraternal And Identical Twins The Same: Twin studies claim that twins are a uniquely powerful genetic laboratory; both fraternal and identical twin pairs have equally concordant environments, but identical twins have more concordant genes. Therefore, the more similar identical twin pairs are relative to fraternal twin pairs, the more heritable a trait must be. But this conclusion falls apart if identical twin pairs actually have more similar environments than fraternal twin pairs do, maybe because parents (knowing their twins are identical) treat them more similarly than they would fraternal twins. Would-be twin-study-discreditors have been trying to argue that this must be true for decades, but it’s always been a kind of quixotic battle. Remember, twin studies find many behavioral traits like IQ are >60% heritable, so you would need to prove not only that parents treat identical twin pairs differently from fraternal, but that this was an overwhelming effect. Parents of identical twins would have to obsessively expose them to the exact same stimuli in the exact same order; parents of fraternal twins would have to send one to the Gifted Advanced Placement Acceleration program while locking the other in a box and force-feeding them lead pellets. Common sense tells us there are no such differences, and studies confirm this: when parents are wrong about their twins’ status (eg they have fraternal twins, but falsely think they’re identical, or vice versa) their trait similarity matches their real status, rather than the incorrect status that determined how their parents treat them; parental treatment explains less than 1% of why identical twin pairs are more concordant (2, 3, 4). See also Felson 2013, which tries to measure environmental similarity and adjust for it, with minimal effects. Are these two cuties monozygotic or dizygotic? Are you sure? (answer) 2: Fraternal And Identical Twins Have Equally Concordant Uterine Environments: Fraternal twins have different sacs in the uterus and use different placentas. Most identical twins share a placenta, and some share an amniotic sac. If trait similarity is caused by sharing a placenta or sac (maybe because the placenta is defective, the fetal brain is starved of nutrients, and so the person has a lower IQ when they grow up), twin studies would falsely read this identical-fraternal difference as genetic. Luckily this is easy to study; not all identical twins share a placenta or sac, so you can cleanly separate the effect of uterine environment from genetics. If you measure enough traits, you can find small deviations in some, but it’s not clear whether this is just multiple testing, and in any case the deviations are small. The best studies suggest this chips off somewhere between 0 - 3% from heritability estimates9. 3: There is little assortative mating: We discussed this one above in the earlier section on GWAS - smart/pretty/kind/whatever people tend to marry other smart/pretty/kind/whatever people. Why would this bias twin study results? Identical twins share 100% of their genes. Fraternal twins ought to share 50% of their genes - but they get half their genes from their mother, and half from their father. In the degenerate case where the mother and father have exactly the same genes (“would you have sex with your clone?”) even fraternal twins will be extremely similar (although not quite identical, since they’ll get different alleles from each clone). In the more plausible case where mothers and fathers are just a little more alike than chance (eg because smart people tend to marry other smart people), fraternal twins will share a genetic tendency towards a trait somewhat more than their 50% shared genes suggest. Since this makes fraternal twin pairs more (genetically) like identical twin pairs, and twin studies assess heritability as the difference in fraternal-identical-twin-pair concordance, this bias would make twin studies underestimate heritability. But this is the opposite of what you would need to “discredit” twin studies - if this bias is true, then everything is more genetic than twin studies think. And unlike the previous two biases, this one seems real and important, so much so that when you adjust for it, the heritability of educational attainment rises from ~40% to ~50%. I’m only mentioning this one here because some anti-hereditarians argue that you can’t trust twin studies because of assortative mating, without mentioning that this can only bias them down. 4: Population stratification: This is often large and worth worrying about, but it applies to identical and fraternal twin pairs equally, and doesn’t bias twin study heritability estimates much (though it might shift the balance between shared and non-shared environment). See eg the sentence around footnote 30 here. 5: Non-additive / “interaction” effects: These are theoretically interesting, but all research thus far has found they are minimal (1, 2). Some experts think this may miss rarer or harder-to-find interactions; we’ll return to this later. 6: “Genetic nurture”, parent-to-child Mentioned above: if there is a gene for reading books to kids, and reading books raises IQ, it will look like a “gene for IQ”. This isn’t as relevant to twin study estimates of heritability, since both identical twins and fraternal twins are equally related to their parents, and any trait caused by genetic nurture wouldn’t differ between them (and therefore would not falsely appear heritable in this design). Rather, they would appear as shared environment. 7: “Genetic nurture”, sibling-to-sibling That is, suppose your sibling’s traits influence your own development. For example, suppose your sibling has a gene that makes them sabotage your schoolwork, causing you to fail and drop out of school early. An identical twin would share this gene with their sibling more often than a fraternal twin, making it look like a “gene for doing badly at school” (since the people who have it do worse at school than those who don’t). Why are we even talking about this? Do we really think it’s a big part of the variance in behavioral traits? Challenging twin study heritability estimates through this route requires inhabiting a weird no-man’s-land where otherwise-invisible genetic and environmental pathways suddenly flare up when you say the magic words “it was done by a sibling”. For example, this requires a strong effect of shared environment - that is, your educational attainment has to depend on whether you’re being sabotaged or not. But in general, shared environmental effects are weak. And it requires a strong effect of genes - that is, this mechanism only works if your sibling’s tendency to sabotage you is highly genetically determined. But we’re deploying this claim to deny that traits like IQ or educational attainment are highly genetically determined. So to get much out of this, the tendency to sabotage siblings would have to be more genetic than other behavioral traits! The reason this convoluted possibility gets brought up so often is that, unlike the more plausible parent-to-child genetic nurture, twin studies can’t rule it out. So if you really want to deny twin studies, this is one of your best bets. But when investigated, this has effects indistinguishable from zero. I’ve been a bit mean in this whole section, because people really like to dismiss twin studies as “Oh, don’t you know, those depend on assumptions, I bet you never considered that assumptions might be wrong”, and then Gish Gallop you with different assumptions until you give up. But scientists have actually done a lot of really good work checking the assumptions and they mostly hold. An alternative way of validating twin studies (brought up by Noah Carl in this article) is to check them against their close cousins, adoption studies and pedigree studies. Pedigree studies investigate large family trees, and check how trait similarity decreases with genetic distance. They avoid twin specific biases (like different treatment of fraternal vs. identical twin pairs, or different prenatal environments), while adding others like assortative mating. Here are the heritabilities of IQ and EA found in pedigree studies10 (see footnote for sources and caveats, and see also here and here for somewhat similar designs): Adoption studies investigate whether adoptees’ traits are more correlated with their adoptive or biological parents. They avoid a large swathe of biases, at the risk of introducing new adoption-related biases of their own (like the possibility that agencies deliberately place adoptive children with parents who are culturally or behaviorally similar, or the possibility that adoptees were adopted late enough to still get some shared environment from their biological parents). Here are the findings of some of the largest and best11: Both straightforwardly confirmed the larger heritability numbers found in twin studies. I would add the evidence from some less formal “adoption studies”12. During residency, I spent a few months working in a child psychiatric hospital for the worst of the worst - kids who committed murder or rape or something before age 18. Many of these children had similar stories: they were taken from their parents just after birth because the parents were criminals/drug addicts/in jail/abusing them. Then they were adopted out to some extremely nice Christian family whose church told them that God wanted them to help poor little children in need. Then they promptly proceeded to commit crime / get addicted to drugs / go to jail / abuse people, all while those families’ biological children were goody-goodies who never got so much as a school detention. When I met with the families, they would always be surprised that things had gone so badly, insisting that they’d raised them exactly like their own son/daughter and taught them good Christian morals. I had to resist the urge to shove a pile of twin studies in their face. This has left me convinced that behavioral traits are highly heritable to a level that it would be hard for any study to contradict. Ultimate source here. Although the study is confusing about this, I think it’s trying to say that almost 90% of subjects were adopted before age 2. But I don’t think studies do contradict this. Given the degree to which their assumptions have been validated, and the level of confirmation from pedigree and adoption studies, I think they have earned a presumption of accuracy. Doubting the twin studies doesn’t seem like a promising route to reconciling the twin-vs-Sib-Regression/RDR discrepancy. What’s Going On? (Part 2: Is Something Wrong With Sib-Regression And RDR?) Sib-Regression is a clever way of avoiding most biases. Its independent variable - the degree to which some sibling pairs end up with slightly more shared genes than others - is even more random and exogenous than the difference between fraternal and identical twins. It can sometimes have biases related to assortative mating (which would falsely push heritability down), but otherwise it’s pretty good. RDR has many of the same advantages, and allows more diverse relationships and so larger sample sizes. It’s hard to think of ways these methods could be wildly off. There is one caveat: although RDR includes most of the rare and structural variants missed by GWAS, in theory it can miss certain ultra-rare variants which are so uncommon that they aren’t shared between some of the relative pairs used in RDR. De novo variants that occurred during the subject’s own conception would be in this category, if the subject didn’t have children or didn’t pass on that gene13. This seems like a pretty small subcategory of genetic variation, and I wouldn’t normally expect that much of importance to be hiding here, but maybe it’s more important than it seems. RDR also doesn’t include much variance caused by statistical interactions between genes. Although we said above that these are usually found to be insignificant, they might be more important in a trait like intelligence that has been under recent evolutionary selection that lops off easily-detectable sources of variance and leaves only the weird obscure ones behind. There’s limited ability for classical Mendelian dominance to affect common variants, but more complicated genetic interactions might still prove important. Overall these are strong methods, and their failure to converge is troubling. If forced to explain them away, we might tell a story like: So far, there is only one RDR study and a few Sib-Regression studies, so we should wait for more data before updating too hard.

Inline links: 5, Polygenic embryo selection, need, Is Tan Et Al The End Of Social Science Genomics?, 6, like, And, 300K, 1M, 3M, A 2016 GREML paper, 7, evolves some ridiculous trick, a Darwinian argument, a 2017 paper, Wainschtein 2022, Sidorenko 2024, Zeng, 8, Weiner 2023, other experts say, meiosis, Young et al (2018), Kemper et al (2021), their trait similarity, matches their real status, 2, 3, 4, Felson 2013, https://substackcdn.com/image/fetch/$s_!r3kV!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd575f2d6-3619-40e6-9a5e-f9f1ec1399a5_650x422.png, answer, The best studies, 9, seems real and important, here, 1, 2, when investigated, in this article, 10, here, here, https://substackcdn.com/image/fetch/$s_!b3LF!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc094f9c0-4c71-48cf-89dc-615498d94812_483x51.png, 11, https://substackcdn.com/image/fetch/$s_!XFWU!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F85f433e5-d141-47b7-8dc5-2271925032e9_483x102.png, 12, https://x.com/cremieuxrecueil/status/1935731422205010135, here, 13

Highlights From The Comments On Missing Heritability

July 03, 2025 · Original source

I think the post conflates gene-gene and gene-environment interactions; the latter (specifically interactions between genes and the "shared" environment) also get counted by twin models as narrow sense heritability. While I agree there is very little evidence for gene-gene interactions (particularly dominance, as you cite [and, interestingly, twin/adoption studies actually forecast a huge amount of dominance -- another discrepancy we do not understand]) there is quote substantial evidence for gene-environment interactions including on educational attainment (see Cheesman et al: https://www.nature.com/articles/s41539-022-00145-8 ; Mostafavi et al: https://elifesciences.org/articles/48376), IQ, and BMI. In fact, Peter Visscher led a paper that came to the conclusion that twin estimates for the heritability of BMI are very likely to be overestimated by gene-environment interactions (https://pubmed.ncbi.nlm.nih.gov/28692066/). A large amount of GxE plus some amount of equal environment violation seems like a very plausible and parsimonious answer to the heritability gap.

Inline links: https://www.nature.com/articles/s41539-022-00145-8, https://elifesciences.org/articles/48376, https://pubmed.ncbi.nlm.nih.gov/28692066/

The horizontal axis is EA4, a polygenic score for predicted educational attainment, generally believed to correlate somewhat with IQ. The vertical axis is observed IQ of each group. Piffer’s point is that different ethnic groups’ predicted genetic intelligence seems to correlate pretty well with their observed intelligence, so maybe group differences in intelligence are genetic. Gusev notes that “every behavior geneticist has been screaming ‘do not do that!’ since the very first study came out”, which is true. I know of three main reasons why this is a bad idea: Polygenic scores will mistake social factors correlated with genetic factors as genetic. For example, in a society where black people have lower IQ because of racism and poor access to schooling, people with a certain gene (the gene for black skin) will have lower IQ. Therefore, a study that blindly correlates genes with IQ will incorrectly assume that the gene for black skin is a gene for IQ/etc. This will ironically seem to justify the original inequality (it will look like black people “only” have low IQ for genetic reasons). This is by far the biggest problem with a plot like this one, and the one Gusev’s post above talks about - and the post offers a good example of a real result on height which encountered this exact problem.

So maybe there’s more of a role here for problems [2] and [3], about the difficulty of applying a score trained on Europeans to non-European populations? My question there is - shouldn’t this produce nonsense results, rather than results which reflect the populations’ real-world IQs? I think the counterargument here would have to be that by coincidence or colonialism, the populations with the furthest genetic difference from Europeans also happen to have the lowest real-world IQs (for social reasons) - or at least that this trend holds in a vague enough way to produce the vague correlation seen on the graph. There’s some evidence for this - this Piffer’s application of EA4 predicts that Chinese (real average IQ 105) have the same educational attainment as Puerto Ricans (real average IQ 82). So maybe it’s just showing average genetic distance from its European sample after all, and Chinese and Puerto Ricans are about equally distant on average? This wouldn’t explain why the predictor correctly finds that Ashkenazi Jews come out highest, but that could be because their “European” sample did include Ashkenazi Jews, and so here problem [1] does come in.

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